INT201948

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Context Info
Confidence 0.27
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Title
Documents 1
Total Number 1
Disease Relevance 0.54
Pain Relevance 0.39

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (DPP4, CXCL10) Golgi apparatus (DPP4) endoplasmic reticulum (DPP4)
cell-cell signaling (CXCL10) peptidase activity (DPP4) extracellular space (CXCL10)
Anatomy Link Frequency
mesenchymal cells 1
DPP4 (Homo sapiens)
CXCL10 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 14 98.52 Very High Very High Very High
cytokine 26 98.00 Very High Very High Very High
chemokine 29 89.32 High High
Arthritis 44 40.56 Quite Low
spinal inflammation 19 35.96 Quite Low
rheumatoid arthritis 22 34.04 Quite Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
psoriasis 1 5.00 Very Low Very Low Very Low
Osteoarthritis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 15 98.52 Very High Very High Very High
Arthropathy 3 95.20 Very High Very High Very High
Cancer 3 83.20 Quite High
Necrosis 3 82.92 Quite High
Arthritis 27 40.56 Quite Low
Low Back Pain 19 35.96 Quite Low
Seronegative Spondarthritis 17 35.00 Quite Low
Rheumatoid Arthritis 22 34.04 Quite Low
Starvation 2 5.00 Very Low Very Low Very Low
Rheumatic Diseases 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Coexpression and interaction of CXCL10 and CD26 in mesenchymal cells by synergising inflammatory cytokines: CXCL8 and CXCL10 are discriminative markers for autoimmune arthropathies

Leukocyte infiltration during acute and chronic inflammation is regulated by exogenous and endogenous factors, including cytokines, chemokines and proteases.

CD26 Binding (interaction) of CXCL10 in mesenchymal cells associated with chemokine, inflammation, arthropathy and cytokine
1) Confidence 0.27 Published 2006 Journal Arthritis Res Ther Section Title Doc Link PMC1779382 Disease Relevance 0.54 Pain Relevance 0.39

General Comments

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