INT202042

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Context Info
Confidence 0.01
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.73
Pain Relevance 1.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (CAMK2N2) peptidase activity (MMP9) extracellular space (MMP9)
extracellular region (MMP9) proteinaceous extracellular matrix (MMP9) nucleus (CAMK2N2)
CAMK2N2 (Homo sapiens)
MMP9 (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 60 100.00 Very High Very High Very High
Arthritis 39 91.72 High High
rheumatoid arthritis 16 86.92 High High
cytokine 4 70.80 Quite High
Inflammation 18 70.40 Quite High
Osteoarthritis 18 53.12 Quite High
Inflammatory marker 1 17.60 Low Low
chemokine 4 5.00 Very Low Very Low Very Low
methotrexate 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Arthritis 44 91.72 High High
Rheumatoid Arthritis 16 86.92 High High
INFLAMMATION 13 70.40 Quite High
Disease 8 68.52 Quite High
Osteoarthritis 19 53.12 Quite High
Rheumatic Diseases 2 5.00 Very Low Very Low Very Low
Ankylosing Spondylitis 1 5.00 Very Low Very Low Very Low
Juvenile Chronic Polyarthritis 1 5.00 Very Low Very Low Very Low
Necrosis 1 5.00 Very Low Very Low Very Low
Seronegative Spondarthritis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These inhibitors have been shown to be selective for two relatively distinct repertoires of MMPs – whereas inhibitor II inhibits MMP-1, MMP-3, MMP-7 and MMP-9, inhibitor III blocks MMP-1, MMP-2, MMP-3, MMP-7 and MMP-13 [26].
inhibitor II Negative_regulation (inhibits) of MMP-9 associated with metalloproteinase
1) Confidence 0.01 Published 2006 Journal Arthritis Res Ther Section Body Doc Link PMC1779417 Disease Relevance 0.73 Pain Relevance 1.25

General Comments

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