INT202161

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Context Info
Confidence 0.31
First Reported 2006
Last Reported 2009
Negated 0
Speculated 1
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 3.36
Pain Relevance 1.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (CSF1R) signal transduction (CSF1R) plasma membrane (CSF1R)
CSF1R (Homo sapiens)
Pain Link Frequency Relevance Heat
Fibrositis 285 100.00 Very High Very High Very High
Migraine 6 99.04 Very High Very High Very High
Inflammation 16 97.40 Very High Very High Very High
spastic colon 7 95.64 Very High Very High Very High
Serotonin 16 89.48 High High
depression 8 85.40 High High
Crohn's disease 1 77.28 Quite High
Pain score 2 65.60 Quite High
Pain 31 38.08 Quite Low
antagonist 3 19.76 Low Low
Disease Link Frequency Relevance Heat
Fibromyalgia 285 100.00 Very High Very High Very High
Headache 7 99.04 Very High Very High Very High
INFLAMMATION 17 97.40 Very High Very High Very High
Functional Bowel Disorder 7 95.64 Very High Very High Very High
Chronic Fatigue Syndrome 22 93.64 High High
Depression 16 85.40 High High
Traumatic Stress Disorders 10 84.48 Quite High
Fatigue 4 80.20 Quite High
Disease 16 77.28 Quite High
Syndrome 33 74.32 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Their results show a significantly different genotype distribution in FMS patients, with a decrease in T/T and an increase in both T/C and C/C genotypes compared to the control population.
Negative_regulation (distribution) of FMS associated with fibrositis
1) Confidence 0.31 Published 2006 Journal Arthritis Res Ther Section Body Doc Link PMC1779444 Disease Relevance 1.05 Pain Relevance 0.58
A high prevalence of FMS was found among female migraine patients [32].
Negative_regulation (prevalence) of FMS associated with migraine and fibrositis
2) Confidence 0.31 Published 2006 Journal Arthritis Res Ther Section Body Doc Link PMC1779444 Disease Relevance 1.54 Pain Relevance 0.41
To explore the possibility that mutations in the MEFV gene may predispose to FMS, we sequenced the regions of likely functional significance in the MEFV gene, exons and splice junctions, in 100 FMS probands and their parents (trios), plus a small number of affected siblings.
Spec (may) Negative_regulation (predispose) of FMS associated with fibrositis
3) Confidence 0.22 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2794536 Disease Relevance 0.77 Pain Relevance 0.23

General Comments

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