INT202166

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Context Info
Confidence 0.38
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.68
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Clec2g)
Anatomy Link Frequency
osteoclast 1
Clec2g (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Pain 4 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
Paresthesia 1 5.00 Very Low Very Low Very Low
Potency 1 5.00 Very Low Very Low Very Low
Bioavailability 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 1 98.12 Very High Very High Very High
Osteoporosis 9 95.56 Very High Very High Very High
Hypercalcemia 3 95.02 Very High Very High Very High
Aseptic Necrosis Of Bone 10 84.16 Quite High
Osteogenesis Imperfecta 1 74.80 Quite High
Bone Disease 6 61.44 Quite High
Cancer 6 53.96 Quite High
Disease 5 48.48 Quite Low
Malignant Neoplastic Disease 1 48.12 Quite Low
Infection 9 46.80 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Bisphosphonates prevent bone resorption by inhibiting osteoclastic activity through different mechanisms: inhibition of osteoclast development from monocytes [42], increased osteoclast apoptosis [42], prevention of osteoclast development and recruitment from bone marrow precursors [43], stimulation of osteoclast inhibitory factor [44], and reduction of osteoclast activity through an effect on the cell cytoskeleton [45].
Positive_regulation (stimulation) of osteoclast inhibitory factor in osteoclast associated with osteoporosis, hypercalcemia and apoptosis
1) Confidence 0.38 Published 2006 Journal Arthritis Res Ther Section Body Doc Link PMC1779450 Disease Relevance 0.68 Pain Relevance 0

General Comments

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