INT202177

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Context Info
Confidence 0.22
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.41
Pain Relevance 0.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (S100A12) extracellular region (S100A12) nucleus (S100A12)
cytoplasm (S100A12)
S100A12 (Homo sapiens)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 90 95.32 Very High Very High Very High
Inflammatory mediators 2 60.08 Quite High
Inflammation 9 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
methotrexate 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 90 95.32 Very High Very High Very High
INFLAMMATION 11 59.68 Quite High
Disease 33 5.00 Very Low Very Low Very Low
Urological Neuroanatomy 7 5.00 Very Low Very Low Very Low
Congenital Anomalies 3 5.00 Very Low Very Low Very Low
Cancer 3 5.00 Very Low Very Low Very Low
Necrosis 2 5.00 Very Low Very Low Very Low
Synovitis 2 5.00 Very Low Very Low Very Low
Cryopyrin-associated Periodic Syndromes 2 5.00 Very Low Very Low Very Low
Hyperplasia 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This process, like S100 protein levels, is likely tied to enhanced secretory activity, in that myeloperoxidase, like S100 proteins, is normally stored in intracellular granules and not released in control cells, although surface expression is seen for some polyarticular JRA neturophils.
Negative_regulation (tied) of Gene_expression (levels) of S100 protein associated with rheumatoid arthritis
1) Confidence 0.22 Published 2006 Journal Arthritis Res Ther Section Body Doc Link PMC1779452 Disease Relevance 0.41 Pain Relevance 0.21

General Comments

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