INT202178

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Context Info
Confidence 0.23
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.98
Pain Relevance 0.44

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (CCL4) extracellular space (CCL4) extracellular region (CCL4)
cell adhesion (CCL4) cell-cell signaling (CCL4)
Anatomy Link Frequency
neutrophils 1
CCL4 (Homo sapiens)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 90 100.00 Very High Very High Very High
Inflammatory mediators 2 100.00 Very High Very High Very High
Inflammation 9 86.76 High High
cytokine 2 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
methotrexate 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 90 100.00 Very High Very High Very High
INFLAMMATION 11 100.00 Very High Very High Very High
Disease 33 90.72 High High
Urological Neuroanatomy 7 12.16 Low Low
Congenital Anomalies 3 5.00 Very Low Very Low Very Low
Cancer 3 5.00 Very Low Very Low Very Low
Necrosis 2 5.00 Very Low Very Low Very Low
Synovitis 2 5.00 Very Low Very Low Very Low
Cryopyrin-associated Periodic Syndromes 2 5.00 Very Low Very Low Very Low
Hyperplasia 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Genes downregulated in JRA neutrophils relative to healthy controls (Table 2) included the immune and inflammatory mediators CCL3, CCL4, CCL5, IL-1B, COX-2, MHC-II DR-?
Negative_regulation (downregulated) of CCL4 in neutrophils associated with inflammatory mediators and rheumatoid arthritis
1) Confidence 0.23 Published 2006 Journal Arthritis Res Ther Section Body Doc Link PMC1779452 Disease Relevance 0.98 Pain Relevance 0.44

General Comments

This test has worked.

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