INT202195

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Context Info
Confidence 0.32
First Reported 2006
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 2.28
Pain Relevance 0.30

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

structural molecule activity (Krt19)
Anatomy Link Frequency
liver 1
Krt19 (Mus musculus)
Pain Link Frequency Relevance Heat
Central nervous system 80 88.48 High High
fibrosis 8 73.88 Quite High
Potency 1 63.60 Quite High
Bile 3 12.08 Low Low
Paracetamol 4 5.00 Very Low Very Low Very Low
Inflammation 3 5.00 Very Low Very Low Very Low
alcohol 3 5.00 Very Low Very Low Very Low
Spinal cord 2 5.00 Very Low Very Low Very Low
palliative 1 5.00 Very Low Very Low Very Low
intrathecal 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Solid Tumor 14 97.40 Very High Very High Very High
Muscle Disease 1 96.16 Very High Very High Very High
Breast Cancer 44 94.12 High High
Apoptosis 23 89.20 High High
Recurrence 37 88.80 High High
Disease 40 87.52 High High
Injury 7 86.40 High High
Gliosis 1 82.64 Quite High
Stress 18 79.84 Quite High
Cancer 35 78.76 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We have previously reported that the use of Transtuzumab could decrease or eradicate CK-19 mRNA-positive CTCs [30].
Negative_regulation (decrease) of CK-19
1) Confidence 0.32 Published 2006 Journal Breast Cancer Res Section Body Doc Link PMC1779464 Disease Relevance 1.28 Pain Relevance 0.23
In contrast, mice lacking K19 did not have an obvious liver phenotype (Tao et al. 2003), but surprisingly exhibited skeletal myopathy (Stone et al. 2007).
Negative_regulation (lacking) of K19 in liver associated with muscle disease
2) Confidence 0.21 Published 2008 Journal Histochem Cell Biol Section Body Doc Link PMC2386529 Disease Relevance 0.99 Pain Relevance 0.07

General Comments

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