INT202208

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Context Info
Confidence 0.74
First Reported 2006
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 3.91
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (GSTT1) cytoplasm (GSTT1)
GSTT1 (Homo sapiens)
Pain Link Frequency Relevance Heat
alcohol 5 22.96 Low Low
Pain 3 5.00 Very Low Very Low Very Low
Angina 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Coronary Artery Disease 110 99.92 Very High Very High Very High
Nicotine Addiction 160 99.10 Very High Very High Very High
Disease Susceptibility 2 90.08 High High
Cancer 36 80.00 Quite High
Disease 21 74.24 Quite High
Toxicity 21 67.92 Quite High
Increased Venous Pressure Under Development 12 67.16 Quite High
Breast Cancer 14 50.00 Quite Low
Atherosclerosis 26 47.12 Quite Low
Recurrence 5 42.96 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The effects of GSTM1/GSTT1 genotype on CAD were augmented when both GSTM1 and GSTT1 genotype were null type (OR, 2.76, CI, 1.17-6.52, p=0.04).
Localization (genotype) of GSTT1 associated with coronary artery disease
1) Confidence 0.74 Published 2008 Journal Journal of Korean Medical Science Section Body Doc Link PMC2526535 Disease Relevance 1.57 Pain Relevance 0
In non-smokers, there was no difference in risk for CAD in relation to GSTM1/GSTT1 genotype (OR, 0.96, CI, 0.56-1.66; OR, 0.77, CI, 0.45-1.31, respectively).
Localization (relation) of GSTT1 associated with coronary artery disease and nicotine addiction
2) Confidence 0.74 Published 2008 Journal Journal of Korean Medical Science Section Body Doc Link PMC2526535 Disease Relevance 1.91 Pain Relevance 0
As described by other publications, individuals with a homozygous deletion of GSTT1 lack the possibility for enzymatic conjugation of environmental carcinogens such as 1,3-butadiene, ethylene oxide, epoxybutanes, methyl bromide, dichloromethane, and monohalomethanes [5-7].
Localization (deletion) of GSTT1
3) Confidence 0.74 Published 2007 Journal Environ Health Section Body Doc Link PMC1802749 Disease Relevance 0.19 Pain Relevance 0
A multiplex PCR technique that detects homozygous deletions of GSTM1 and GSTT1 was used, including primers for the ?
Localization (deletions) of GSTT1
4) Confidence 0.70 Published 2006 Journal Breast Cancer Res Section Body Doc Link PMC1779469 Disease Relevance 0.24 Pain Relevance 0

General Comments

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