INT202249

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Context Info
Confidence 0.35
First Reported 2006
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 23
Total Number 23
Disease Relevance 14.93
Pain Relevance 0.63

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Mention Frequency
coronary artery 2
plasma 1
HomA (Helicobacter felis)
Pain Term Frequency Confidence Heat
cytokine 48 89.68 High High
anesthesia 102 75.00 Quite High
headache 6 74.76 Quite High
Pain 6 73.84 Quite High
Inflammation 146 69.36 Quite High
beta blocker 2 60.12 Quite High
cINOD 6 16.80 Low Low
imagery 10 14.64 Low Low
corticosteroid 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Disease Term Frequency Confidence Heat
Hyperinsulinism 31 100.00 Very High Very High Very High
Malaria 128 99.76 Very High Very High Very High
Coronary Artery Disease 180 99.68 Very High Very High Very High
[[ /

[[]]]]

7 99.20 Very High Very High Very High
Nicotine Addiction 12 98.56 Very High Very High Very High
Pressure And Volume Under Development 4 98.20 Very High Very High Very High
Myocardial Infarction 40 98.12 Very High Very High Very High
Apnoea 534 97.92 Very High Very High Very High
Convulsion 22 97.60 Very High Very High Very High
Insulin Resistance 298 97.60 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Physical constitution was rather seen as a cause of homa than malaria.
Positive_regulation (cause) of homa associated with malaria
1) Confidence 0.35 Published 2008 Journal BMC Public Health Section Body Doc Link PMC2564938 Disease Relevance 1.47 Pain Relevance 0
The physical constitution of a child was rather seen as a cause of homa than malaria (P = 0.023).
Positive_regulation (cause) of homa associated with malaria
2) Confidence 0.24 Published 2008 Journal BMC Public Health Section Body Doc Link PMC2564938 Disease Relevance 1.81 Pain Relevance 0.15
SaO2, and SD and CV of oxyhemoglobin saturation during sleep were significantly linearly associated with increased HOMA-B in subjects with NGM independent of sex and BMI.
Positive_regulation (increased) of HOMA
3) Confidence 0.06 Published 2010 Journal Cardiovasc Diabetol Section Body Doc Link PMC3002325 Disease Relevance 0.25 Pain Relevance 0
There were trends towards increased insulin levels (P = 0.069) and increased HOMA-IR (P = 0.050) in the case group.
Positive_regulation (increased) of HOMA associated with hyperinsulinism
4) Confidence 0.05 Published 2010 Journal Cardiovasc Diabetol Section Body Doc Link PMC3002325 Disease Relevance 0.49 Pain Relevance 0.04
Even after adjusting for sex and BMI, the increases in AHI in subjects with NGM were associated with increases in HOMA-B (P < 0.001), HOMA-IR (P < 0.001), and insulin levels (P < 0.001).
Positive_regulation (increases) of HOMA
5) Confidence 0.04 Published 2010 Journal Cardiovasc Diabetol Section Body Doc Link PMC3002325 Disease Relevance 0.30 Pain Relevance 0
Bivariate and linear regression analyses (Table 2 and Figure 2) confirmed that increases in HOMA-B and insulin levels were strongly associated with OSA severity in both men and women with NGM and for the NGM group as a whole.
Positive_regulation (increases) of HOMA associated with apnoea
6) Confidence 0.04 Published 2010 Journal Cardiovasc Diabetol Section Body Doc Link PMC3002325 Disease Relevance 0.30 Pain Relevance 0
Even after adjusting for sex and BMI, the increases in AHI in subjects with NGM were associated with increases in HOMA-B (P < 0.001), HOMA-IR (P < 0.001), and insulin levels (P < 0.001).
Positive_regulation (increases) of HOMA
7) Confidence 0.04 Published 2010 Journal Cardiovasc Diabetol Section Body Doc Link PMC3002325 Disease Relevance 0.30 Pain Relevance 0
HOMA2 models could not be calculated for one man with NGM (missing insulin data) and for three women with IGM.
Neg (not) Positive_regulation (calculated) of HOMA2
8) Confidence 0.04 Published 2010 Journal Cardiovasc Diabetol Section Body Doc Link PMC3002325 Disease Relevance 0.34 Pain Relevance 0
As has been observed previously in CONV C57BL/6 mice, HF diet was associated with dramatic elevations in plasma insulin and HOMA but only after 16 weeks of diet (Figure 3A and 3C).
Positive_regulation (elevations) of HOMA in plasma
9) Confidence 0.04 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2922379 Disease Relevance 0.64 Pain Relevance 0.03
HOMA was increased (from 0.8 to 3.7) but did not reach significance (p = 0.07, Figure 4 &9).
Positive_regulation (increased) of HOMA
10) Confidence 0.04 Published 2007 Journal Nutr Metab (Lond) Section Body Doc Link PMC1779788 Disease Relevance 0 Pain Relevance 0.07
From baseline to the first postoperative day there was a significant increase in group B and C in HOMA (from 0.8 to1.3 and 1.2 to1.8 respectively; p < 0.05, Figure 9) and IGFBP-1 (from 35 to45 ?
Positive_regulation (increase) of HOMA
11) Confidence 0.04 Published 2007 Journal Nutr Metab (Lond) Section Body Doc Link PMC1779788 Disease Relevance 0 Pain Relevance 0
Liraglutide monotherapy increased HOMA compared with metformin therapy (3.3%, P = 0.0001).
Positive_regulation (increased) of HOMA
12) Confidence 0.03 Published 2010 Journal Drug Design, Development and Therapy Section Body Doc Link PMC2990388 Disease Relevance 0.35 Pain Relevance 0
CONV mice became overtly insulin resistant as manifest by increased HOMA by 16 weeks after onset of HF diet.
Positive_regulation (increased) of HOMA
13) Confidence 0.03 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2922379 Disease Relevance 1.43 Pain Relevance 0.06
As predicted, the results were that the higher value of HOMA-IR was associated with the higher incidence of MACE, since more TVR was performed in cases with higher value of HOMA-IR.
Positive_regulation (value) of HOMA
14) Confidence 0.03 Published 2006 Journal Journal of Korean Medical Science Section Body Doc Link PMC2733993 Disease Relevance 1.54 Pain Relevance 0
In particular, amino acid infusion before and during surgery totally abolished the increase in insulin, and diminished the increase in IGFBP-1 and HOMA seen in the other operated groups on the first postoperative day.
Positive_regulation (increase) of HOMA
15) Confidence 0.03 Published 2007 Journal Nutr Metab (Lond) Section Body Doc Link PMC1779788 Disease Relevance 0.67 Pain Relevance 0
From baseline to the first postoperative day there was a significant increase in HOMA and IGFBP-1 in groups B and C.
Positive_regulation (increase) of HOMA
16) Confidence 0.03 Published 2007 Journal Nutr Metab (Lond) Section Abstract Doc Link PMC1779788 Disease Relevance 0.23 Pain Relevance 0.25
Increased HOMA values were not statistically significantly associated with postoperative mortality when compared to the lower three quartiles (30-day adjusted OR 1.7 [95% CI 0.5-5.7] and 31-365-days adjusted OR 1.7 [95% CI 0.7-3.3]) (Figure 1).
Positive_regulation (Increased) of HOMA
17) Confidence 0.03 Published 2010 Journal J Cardiothorac Surg Section Body Doc Link PMC3009968 Disease Relevance 0.29 Pain Relevance 0.03
The liraglutide groups had improvements in HOMA (?
Positive_regulation (improvements) of HOMA
18) Confidence 0.03 Published 2010 Journal Drug Design, Development and Therapy Section Body Doc Link PMC2990388 Disease Relevance 0.33 Pain Relevance 0
In one study, increased HOMA-IR was associated with an increased incidence of myocardial infarction and death, even when the cardiovascular risk was adjusted for smoking and low physical activity.
Positive_regulation (increased) of HOMA-IR associated with nicotine addiction, death and myocardial infarction
19) Confidence 0.01 Published 2010 Journal Diabetol Metab Syndr Section Body Doc Link PMC2830967 Disease Relevance 1.02 Pain Relevance 0
TG/HDLc index and HOMA-IR were significantly increased in the CAD group (Figure 1), as compared to the No CAD group, (p = 0.0446 and p = 0.0152, respectively).
Positive_regulation (increased) of HOMA-IR associated with coronary artery disease
20) Confidence 0.01 Published 2010 Journal Diabetol Metab Syndr Section Body Doc Link PMC2830967 Disease Relevance 1.34 Pain Relevance 0

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