INT202262

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Context Info
Confidence 0.25
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.57
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitosis (Pttg1) chromosome organization (Pttg1) chromosome segregation (Pttg1)
nucleus (Pttg1) cell cycle (Pttg1) cell division (Pttg1)
Anatomy Link Frequency
pituitary 2
Pttg1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Dopamine 31 79.76 Quite High
metalloproteinase 1 44.56 Quite Low
agonist 8 38.60 Quite Low
imagery 6 5.00 Very Low Very Low Very Low
dopamine receptor 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pituitary Cancer 34 100.00 Very High Very High Very High
Cancer 60 89.04 High High
Apoptosis 11 80.80 Quite High
Prolactinoma 43 75.28 Quite High
Hyperplasia 13 69.64 Quite High
Hypoxia 4 69.16 Quite High
Aging 6 60.44 Quite High
Galactorrhea 6 59.76 Quite High
Death 2 59.72 Quite High
Targeted Disruption 22 9.84 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Experimentally, PTTG has also been shown to be regulated by exposure to estrogen [23, 39] and our results demonstrated that lowered levels of PTTG were observed in the E2+G6-31 group.
Negative_regulation (lowered) of Gene_expression (levels) of PTTG
1) Confidence 0.25 Published 2010 Journal Acta Histochemica et Cytochemica Section Body Doc Link PMC2875861 Disease Relevance 0.66 Pain Relevance 0
In fact, abundant and concordant PTTG and bFGF expression in different human pituitary tumors was described [4].
Negative_regulation (described) of Gene_expression (expression) of PTTG in pituitary associated with pituitary cancer
2) Confidence 0.23 Published 2007 Journal Mol Cancer Section Body Doc Link PMC1779802 Disease Relevance 0.91 Pain Relevance 0.12

General Comments

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