INT202369

Context Info Confidence 0.74 First Reported 2007 Last Reported 2007 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.06 Pain Relevance 0

protein complex (Ccm2) cytoplasm (Ccm2)

Ccm2 (Mus musculus)

Pain Link Frequency Relevance Heat cytokine 2 5.00 depression 1 5.00 cINOD 1 5.00 imagery 1 5.00

Disease Link Frequency Relevance Heat Stress 8 63.72 Increased Venous Pressure Under Development 4 5.00 Congenital Anomalies 2 5.00 Reprotox - General 3 1 5.00 Depression 1 5.00 Shock 1 5.00 INFLAMMATION 1 5.00 Carcinoma 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Though changes were not detected in localization or steady state mRNA transcript levels of CCM2 following hyperosmotic treatment, our results did reveal a significant increase in CCM2 immunofluorescence in blastocysts treated for 15 minutes in 0.2 M sorbitol (460 mOsm), but not 1.4% glycerol (460 mOsm).

Localization (localization) of CCM2

1) Confidence 0.74 Published 2007 Journal BMC Dev Biol Section Body Doc Link PMC1781062 Disease Relevance 0.06 Pain Relevance 0

General Comments

This test has worked.