INT202386

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Context Info
Confidence 0.69
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 6
Disease Relevance 0.15
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Map2k4) nucleus (Map2k4) kinase activity (Map2k4)
response to stress (Map2k4) cytoplasm (Map2k4)
Anatomy Link Frequency
2-cell stage 1
Map2k4 (Mus musculus)
Pain Link Frequency Relevance Heat
cINOD 6 21.00 Low Low
cytokine 12 19.56 Low Low
depression 6 5.00 Very Low Very Low Very Low
imagery 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Congenital Anomalies 12 76.44 Quite High
Shock 6 34.04 Quite Low
INFLAMMATION 6 20.76 Low Low
Stress 48 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 24 5.00 Very Low Very Low Very Low
Reprotox - General 3 6 5.00 Very Low Very Low Very Low
Depression 6 5.00 Very Low Very Low Very Low
Carcinoma 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Qualitative RT-PCR methods resulted in the detection of mRNA transcripts encoding Ccm2, Map3k3, Map2k3, Map2k6 and Map2k4 producing the expected size amplicons of 371 bp, 374 bp, 387 bp, 395 bp and 363 bp respectively throughout mouse preimplantation development in all 3 experimental replicates (Figure 2A).
Transcription (detection) of Map2k4
1) Confidence 0.69 Published 2007 Journal BMC Dev Biol Section Body Doc Link PMC1781062 Disease Relevance 0.07 Pain Relevance 0
Conversely, the relatively low expression of Map2k4 mRNA transcripts past the 1-cell stage suggests a reduced role for this kinase during early development.
Transcription (expression) of Map2k4
2) Confidence 0.51 Published 2007 Journal BMC Dev Biol Section Body Doc Link PMC1781062 Disease Relevance 0 Pain Relevance 0
Map2k4 mRNA levels then remained low throughout preimplantation development, but did increase significantly (P ?
Transcription (levels) of Map2k4
3) Confidence 0.51 Published 2007 Journal BMC Dev Biol Section Body Doc Link PMC1781062 Disease Relevance 0 Pain Relevance 0
Conversely, the relatively low expression of Map2k4 mRNA transcripts past the 1-cell stage suggests a reduced role for this kinase during early development.
Transcription (transcripts) of Map2k4
4) Confidence 0.51 Published 2007 Journal BMC Dev Biol Section Body Doc Link PMC1781062 Disease Relevance 0 Pain Relevance 0
In contrast, Map2k4 (Figure 2F) steady state mRNA levels were highest at the 1-cell stage and declined significantly at the 2-cell stage (P ?
Transcription (levels) of Map2k4 in 2-cell stage
5) Confidence 0.44 Published 2007 Journal BMC Dev Biol Section Body Doc Link PMC1781062 Disease Relevance 0 Pain Relevance 0
Detection of mRNA transcripts encoding Ccm2, Map3k3, Map2k3, Map2k6, and Map2k4 during mouse preimplantation development
Transcription (Detection) of Map2k4
6) Confidence 0.44 Published 2007 Journal BMC Dev Biol Section Body Doc Link PMC1781062 Disease Relevance 0.08 Pain Relevance 0

General Comments

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