INT202422

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Context Info
Confidence 0.02
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.91
Pain Relevance 0.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (IL8, ELANE) peptidase activity (ELANE) signal transduction (IL8)
extracellular space (IL8) intracellular (IL8) cytoplasm (ELANE)
Anatomy Link Frequency
neutrophils 2
IL8 (Homo sapiens)
ELANE (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 34 90.56 High High
Inflammatory response 7 89.60 High High
Inflammation 35 46.52 Quite Low
fibrosis 9 5.00 Very Low Very Low Very Low
Inflammatory mediators 3 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Versed 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Bronchiectasis 70 95.68 Very High Very High Very High
Disease 6 95.44 Very High Very High Very High
INFLAMMATION 45 89.24 High High
Necrosis 3 87.40 High High
Apoptosis 3 85.96 High High
Pulmonary Disease 13 47.52 Quite Low
Cancer 2 34.28 Quite Low
Infection 8 5.00 Very Low Very Low Very Low
Cystic Fibrosis 6 5.00 Very Low Very Low Very Low
Injury 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Since IL-8 can activate neutrophils by increasing degranulation and neutrophil elastase release, our attention has been focused on its pivotal and fundamental responsibility for bronchial destruction in bronchiectasis due to sulfur mustard gas inhalation [30].
IL-8 Positive_regulation (increasing) of Localization (release) of neutrophil elastase in neutrophils associated with bronchiectasis
1) Confidence 0.02 Published 2007 Journal J Inflamm (Lond) Section Body Doc Link PMC1781448 Disease Relevance 0.91 Pain Relevance 0.24

General Comments

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