INT202489

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Context Info
Confidence 0.53
First Reported 2007
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 1.63
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Chuk) nucleus (Chuk) kinase activity (Chuk)
cytoplasm (Chuk)
Anatomy Link Frequency
B-cell 1
Chuk (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 22 82.52 Quite High
Inflammation 32 82.12 Quite High
Inflammatory response 10 35.44 Quite Low
chemokine 14 5.00 Very Low Very Low Very Low
cINOD 4 5.00 Very Low Very Low Very Low
Inflammatory mediators 4 5.00 Very Low Very Low Very Low
COX2 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
addiction 2 5.00 Very Low Very Low Very Low
Glutamate 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Infection 196 98.64 Very High Very High Very High
Cancer 8 91.36 High High
Death 6 90.08 High High
Pox Virus Infection 18 84.84 Quite High
Necrosis 4 83.40 Quite High
INFLAMMATION 50 82.12 Quite High
Epstein-barr Virus 26 67.84 Quite High
Sprains And Strains 10 57.84 Quite High
Targeted Disruption 30 50.96 Quite High
Lymphatic System Cancer 6 33.64 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
M might reflect (i) the utilization of alternative NIK/IKK1-mediated NF-?
Localization (utilization) of IKK1
1) Confidence 0.53 Published 2007 Journal PLoS Pathogens Section Body Doc Link PMC1781481 Disease Relevance 0.33 Pain Relevance 0
receptor and the B-cell–activating factor of the TNF family (BAFF) leads to the release of p52:RelB dimers via the alternative IKK1/NIK-dependent pathway (reviewed in [12]).
Localization (release) of IKK1 in B-cell
2) Confidence 0.23 Published 2007 Journal PLoS Pathogens Section Body Doc Link PMC1781481 Disease Relevance 0.43 Pain Relevance 0.08
, or NEMO was observed (Figure 2B), although FLAG-B14 and IKK?
Localization (observed) of IKK
3) Confidence 0.20 Published 2008 Journal PLoS Pathogens Section Body Doc Link PMC2233672 Disease Relevance 0 Pain Relevance 0
B14 functions by interacting with a cellular protein called IKK?
Localization (called) of IKK
4) Confidence 0.20 Published 2008 Journal PLoS Pathogens Section Abstract Doc Link PMC2233672 Disease Relevance 0.87 Pain Relevance 0

General Comments

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