INT202491

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Context Info
Confidence 0.42
First Reported 2007
Last Reported 2008
Negated 1
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.29
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
marginal zone 2
memory B cell 2
Cd19 (Mus musculus)
Pain Link Frequency Relevance Heat
addiction 1 79.92 Quite High
cytokine 29 52.32 Quite High
Inflammation 11 5.00 Very Low Very Low Very Low
chemokine 5 5.00 Very Low Very Low Very Low
fibrosis 4 5.00 Very Low Very Low Very Low
imagery 3 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Inflammatory marker 2 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
headache 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Lymphatic System Cancer 62 99.98 Very High Very High Very High
B-cell Chronic Lymphocytic Leukemia 12 98.92 Very High Very High Very High
B-cell Lymphoma 2 86.88 High High
Follicular Lymphoma 25 81.00 Quite High
Infection 122 73.24 Quite High
Residual Neoplasm 1 55.12 Quite High
Retroviridae Infections 1 54.36 Quite High
Mantle-cell Lymphoma 17 35.84 Quite Low
Genetic Translocation 1 24.88 Low Low
Epstein-barr Virus 37 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The frequency of latently infected CD19?
Positive_regulation (infected) of Gene_expression (infected) of CD19
1) Confidence 0.42 Published 2007 Journal PLoS Pathogens Section Body Doc Link PMC1781481 Disease Relevance 0.07 Pain Relevance 0.04
Together, these data provide strong evidence that M2 expression leads to B cell activation and differentiation similar to a functional activated, pre-plasma memory B cell phenotype, namely CD19+, sIgG+, sIgD?
Positive_regulation (activated) of Gene_expression (phenotype) of CD19 in memory B cell
2) Confidence 0.30 Published 2008 Journal PLoS Pathogens Section Body Doc Link PMC2270344 Disease Relevance 0.05 Pain Relevance 0.05
The immunophenotype of marginal lymphomas is distinct from other small lymphocytic lymphomas: the antigen profile for the marginal zone lymphomas include CD19, CD20, CD22 positive and CD5, CD10, CD23, and CD11C negative.
Positive_regulation (include) of Neg (negative) Gene_expression (negative) of CD19 in marginal zone associated with b-cell chronic lymphocytic leukemia and lymphatic system cancer
3) Confidence 0.19 Published 2007 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2721318 Disease Relevance 1.16 Pain Relevance 0

General Comments

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