INT202581

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Context Info
Confidence 0.49
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.81
Pain Relevance 0.47

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

pigmentation (DRD2) plasma membrane (DRD2) signal transducer activity (DRD2)
Anatomy Link Frequency
striatum 2
DRD2 (Homo sapiens)
Pain Link Frequency Relevance Heat
positron emission tomography 46 97.92 Very High Very High Very High
Dopamine 89 88.72 High High
imagery 24 80.36 Quite High
Substantia nigra 6 51.68 Quite High
monoamine 6 5.00 Very Low Very Low Very Low
midbrain 5 5.00 Very Low Very Low Very Low
Neurotransmitter 4 5.00 Very Low Very Low Very Low
addiction 4 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 67 99.50 Very High Very High Very High
Parkinsonian Disorders 39 91.36 High High
Liver Disease 12 78.92 Quite High
Attention Deficit Hyperactivity Disorder 80 68.52 Quite High
Congenital Anomalies 15 67.20 Quite High
Neurodegenerative Disease 2 28.32 Quite Low
Tremor 12 5.00 Very Low Very Low Very Low
Nerve Degeneration 7 5.00 Very Low Very Low Very Low
Hypokinesia 5 5.00 Very Low Very Low Very Low
Drug Induced Neurotoxicity 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Repeating the principal analyses in the largest single racial group, those with European ancestry, the main effect of DRD2 on DDT k values was marginally significant (F (1,74) = 3.487, p = .066, ?
Positive_regulation (on) of Gene_expression (effect) of DRD2
1) Confidence 0.49 Published 2007 Journal Behav Brain Funct Section Body Doc Link PMC1781951 Disease Relevance 0.07 Pain Relevance 0
Importantly, PD patients have normal or increased levels of D2R in the striatum (Table 2).
Positive_regulation (increased) of Gene_expression (levels) of D2R in striatum associated with disease
2) Confidence 0.42 Published 2010 Journal Environ Health Perspect Section Body Doc Link PMC2920085 Disease Relevance 0.74 Pain Relevance 0.47

General Comments

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