INT202640

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Context Info
Confidence 0.39
First Reported 2007
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 1.08
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Mycn) DNA binding (Mycn)
Anatomy Link Frequency
lung 1
Mycn (Mus musculus)
Pain Link Frequency Relevance Heat
anesthesia 2 63.32 Quite High
ketamine 2 59.00 Quite High
fibrosis 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
Chronic pancreatitis 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Death 6 94.68 High High
Recurrence 2 88.04 High High
Cancer 138 88.00 High High
Neuroblastoma 126 70.20 Quite High
Dislocations 2 62.44 Quite High
Body Weight 2 32.56 Quite Low
Necrosis 2 12.04 Low Low
Targeted Disruption 20 5.00 Very Low Very Low Very Low
Apoptosis 16 5.00 Very Low Very Low Very Low
Disease 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Consistent with this, N-myc was only recently shown to be a direct target of Wnt signaling in the lung [10].
Gene_expression (target) of N-myc in lung
1) Confidence 0.39 Published 2007 Journal BMC Dev Biol Section Body Doc Link PMC1783845 Disease Relevance 0 Pain Relevance 0
High CHD5 expression was strongly associated with favorable clinical and biologic features: younger age (either <12 or <18 months), lower stage (1, 2, 4S vs 3 and 4), non-amplified MYCN, hyperdiploidy, favorable histopathology, and normal 11q (Table 1) (P < .001 for all).
Gene_expression (expression) of MYCN
2) Confidence 0.38 Published 2008 Journal JNCI Journal of the National Cancer Institute Section Body Doc Link PMC2483574 Disease Relevance 0.62 Pain Relevance 0
We used Cox regression models to examine the prognostic significance of CHD5 expression, 1p deletion, and MYCN amplification.
Gene_expression (expression) of MYCN
3) Confidence 0.38 Published 2008 Journal JNCI Journal of the National Cancer Institute Section Body Doc Link PMC2483574 Disease Relevance 0.46 Pain Relevance 0.09

General Comments

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