INT202702

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Context Info
Confidence 0.36
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 4
Disease Relevance 3.82
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (IGF2BP3) RNA binding (IGF2BP3) nucleus (IGF2BP3)
translation (IGF2BP3) cytoplasm (IGF2BP3)
IGF2BP3 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 25 77.76 Quite High
fibrosis 1 72.40 Quite High
Lasting pain 2 45.36 Quite Low
Pain 5 43.76 Quite Low
antagonist 3 11.12 Low Low
Chronic pancreatitis 3 5.00 Very Low Very Low Very Low
imagery 3 5.00 Very Low Very Low Very Low
backache 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 112 98.60 Very High Very High Very High
Adenocarcinoma 75 96.72 Very High Very High Very High
Disease 16 92.44 High High
Body Weight 1 84.68 Quite High
Growth Problems 5 83.88 Quite High
Leukemia 3 79.84 Quite High
Phosphate Metabolism Disorders 34 79.68 Quite High
INFLAMMATION 20 77.76 Quite High
Osteomyelitis 20 75.84 Quite High
Malignant Neoplastic Disease 16 72.96 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Insulin-like growth factor 2 mRNA binding protein 3 (IGF2BP3, also known as IMP3 or KOC) is an oncofetal RNA-binding protein that regulates targets such as insulin-like growth factor-2 (IGF-2) and ACTB (beta-actin).


Insulin-like growth factor 2 mRNA binding protein 3 Binding (binding) of
1) Confidence 0.36 Published 2010 Journal BMC Cancer Section Abstract Doc Link PMC2837867 Disease Relevance 0.70 Pain Relevance 0
Insulin-like growth factor 2 mRNA binding protein 3 (IGF2BP3, also known as IMP3 or KOC) is an oncofetal RNA-binding protein that regulates targets such as insulin-like growth factor-2 (IGF-2) and ACTB (beta-actin).


IGF2BP3 Binding (binding) of
2) Confidence 0.36 Published 2010 Journal BMC Cancer Section Abstract Doc Link PMC2837867 Disease Relevance 0.70 Pain Relevance 0
If this hypothesis holds true, IGF2BP3 could be regarded as a target for re-methylating enzymes.
IGF2BP3 Binding (target) of
3) Confidence 0.36 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2837867 Disease Relevance 0.97 Pain Relevance 0
A detailed diagnostic workup repetitively revealed a normal concentration of IgF1 (insulin-like growth factor), IgF BP-3 (insulin-like growth factor binding protein).
IgF BP-3 Binding (concentration) of
4) Confidence 0.17 Published 2007 Journal BMC Pediatr Section Body Doc Link PMC1784091 Disease Relevance 1.46 Pain Relevance 0.08

General Comments

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