INT202716

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Context Info
Confidence 0.49
First Reported 2007
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 5
Disease Relevance 4.56
Pain Relevance 0.57

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (NMS)
Anatomy Link Frequency
spinal 2
muscle 1
NMS (Homo sapiens)
Pain Link Frequency Relevance Heat
hyperexcitability 2 89.52 High High
Pain 25 86.48 High High
backache 63 86.04 High High
Neurotransmitter 8 80.60 Quite High
Acupuncture 18 66.20 Quite High
Dopamine 8 62.84 Quite High
Antihistamine 1 60.00 Quite High
antidepressant 1 57.12 Quite High
complementary and alternative medicine 261 51.60 Quite High
Serotonin 27 47.84 Quite Low
Disease Link Frequency Relevance Heat
Neuroleptic Malignant Syndrome 90 100.00 Very High Very High Very High
Delirium 59 100.00 Very High Very High Very High
Catatonia 35 99.80 Very High Very High Very High
Volume Depletion And Dehydration 2 96.20 Very High Very High Very High
Fever 68 94.76 High High
Heart Rate Under Development 7 94.48 High High
Hypertension 2 93.96 High High
Toxicity 6 92.76 High High
Death 7 91.80 High High
Sudden Death 2 91.08 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It is noteworthy that excited delirium, NMS and catatonia may result in many physical symptoms that are similar such as profuse sweating, dehydration, electrolyte imbalance, fever, tachycardia, hypertension, rapid breathing, and the possibility of death without proper treatment.9,14,32,48–50
Gene_expression (delirium) of NMS associated with heart rate under development, catatonia, neuroleptic malignant syndrome, hypertension, volume depletion and dehydration, delirium, fever and death
1) Confidence 0.49 Published 2009 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2695211 Disease Relevance 1.84 Pain Relevance 0.03
In other studies modeling the complete human NMS system, the spinal network is simply neglected or extremely simplified, although a few models exist on animal NMS systems (e.g.
Gene_expression (exist) of NMS in spinal associated with neuroleptic malignant syndrome
2) Confidence 0.29 Published 2007 Journal J Comput Neurosci Section Body Doc Link PMC2799624 Disease Relevance 0.57 Pain Relevance 0.08
In other studies modeling the complete human NMS system, the spinal network is simply neglected or extremely simplified, although a few models exist on animal NMS systems (e.g.
Gene_expression (system) of NMS in spinal associated with neuroleptic malignant syndrome
3) Confidence 0.29 Published 2007 Journal J Comput Neurosci Section Body Doc Link PMC2799624 Disease Relevance 0.54 Pain Relevance 0.09
As a supposed mechanism of heat production in NMS points to presynaptic involvement, a further therapeutic option includes mechanical ventilation and muscle relaxation in severe cases, which may result in rapid lowering of increased muscle activity and heat production [33].


Gene_expression (production) of NMS in muscle associated with neuroleptic malignant syndrome
4) Confidence 0.27 Published 2007 Journal Crit Care Section Body Doc Link PMC2246210 Disease Relevance 0.91 Pain Relevance 0.06
Four cohorts were examined: (1) patients in health plans that covered chiropractic and who received any treatment (DC or MD) for a NMS condition; (2) Patients in plans that did not cover chiropractic and who were treated for NMS conditions; (3) Patients in plans that covered chiropractic and who received a chiropractic treatment for an NMS condition; and (4) Patients in health plans that covered chiropractic but who received medical treatment for NMS conditions.
Gene_expression (condition) of NMS associated with neuroleptic malignant syndrome
5) Confidence 0.04 Published 2007 Journal Chiropr Osteopat Section Body Doc Link PMC1784103 Disease Relevance 0.70 Pain Relevance 0.32

General Comments

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