INT202805

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Context Info
Confidence 0.41
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.77
Pain Relevance 0.43

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

isomerase activity (Pin1) protein folding (Pin1) nucleus (Pin1)
cell cycle (Pin1) cytoplasm (Pin1)
Pin1 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 60 99.98 Very High Very High Very High
Inflammation 12 94.80 High High
fibrosis 4 89.36 High High
corticosteroid 2 80.56 Quite High
chemokine 4 76.24 Quite High
isoflurane 10 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Thoracotomy 2 5.00 Very Low Very Low Very Low
Multiple sclerosis 2 5.00 Very Low Very Low Very Low
cva 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Graft Vs Host Disease 12 99.24 Very High Very High Very High
INFLAMMATION 12 94.80 High High
Congenital Anomalies 2 91.84 High High
Targeted Disruption 32 90.92 High High
Fibrosis 4 89.36 High High
Toxicity 8 85.84 High High
Cytomegalovirus Infection 2 78.36 Quite High
Cancer 4 5.00 Very Low Very Low Very Low
Demyelinating Disease 2 5.00 Very Low Very Low Very Low
Overdose 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Irrespective of molecular mechanism, suppression of Pin1 clearly prevented acute and chronic graft rejection.
Negative_regulation (prevented) of Negative_regulation (suppression) of Pin1 associated with graft vs host disease
1) Confidence 0.41 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1790862 Disease Relevance 0.46 Pain Relevance 0.20
and CXCL-10 in the process of acute rejection and suggest that cytokine suppression after Pin1 inhibition is likely responsible for graft sparing.
Negative_regulation (suppression) of Negative_regulation (inhibition) of Pin1 associated with cytokine
2) Confidence 0.41 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1790862 Disease Relevance 0.31 Pain Relevance 0.22

General Comments

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