INT202808

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Context Info
Confidence 0.08
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.84
Pain Relevance 0.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Pin1, Hnrpd) nucleus (Pin1, Hnrpd) isomerase activity (Pin1)
cytosol (Hnrpd) protein folding (Pin1) nucleocytoplasmic transport (Hnrpd)
Pin1 (Mus musculus)
Hnrpd (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cytokine 60 98.08 Very High Very High Very High
cva 2 77.92 Quite High
fibrosis 4 60.52 Quite High
Multiple sclerosis 2 58.56 Quite High
isoflurane 10 34.24 Quite Low
corticosteroid 2 30.48 Quite Low
Inflammation 12 5.00 Very Low Very Low Very Low
chemokine 4 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Thoracotomy 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Toxicity 8 92.32 High High
Graft Vs Host Disease 12 88.20 High High
Hemorrhage 2 77.92 Quite High
Communicable Diseases 2 65.20 Quite High
Targeted Disruption 32 61.68 Quite High
Fibrosis 4 60.52 Quite High
Autoimmune Disease 2 60.48 Quite High
Diabetes Mellitus 2 59.36 Quite High
Demyelinating Disease 2 58.56 Quite High
Systemic Lupus Erythematosus 2 56.72 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Mechanistically, Pin1 interacts with and controls the ARE mRNA-binding activity of AUF1.
Pin1 Binding (activity) of AUF1
1) Confidence 0.08 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1790862 Disease Relevance 0.14 Pain Relevance 0.08
Based on prior work, Pin1 likely functions through direct interactions with and regulation of key AUUUA specific, mRNA binding proteins such as AUF1, HnRNP C and HuR [12], [13].
Pin1 Binding (interactions) of AUF1
2) Confidence 0.08 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1790862 Disease Relevance 0.70 Pain Relevance 0.15

General Comments

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