INT202924

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Context Info
Confidence 0.69
First Reported 2007
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.12
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Fbn1) proteinaceous extracellular matrix (Fbn1)
Anatomy Link Frequency
TSK 1
body 1
Fbn1 (Mus musculus)
Pain Link Frequency Relevance Heat
fibrosis 29 82.48 Quite High
cytokine 3 54.36 Quite High
ketamine 3 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
cva 2 5.00 Very Low Very Low Very Low
Analgesic 1 5.00 Very Low Very Low Very Low
amygdala 1 5.00 Very Low Very Low Very Low
Hippocampus 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Systemic Sclerosis 18 84.00 Quite High
Keloid Scars 1 82.48 Quite High
Mixed Connective Tissue Disorder 2 73.92 Quite High
Cardiovascular Disease 4 72.92 Quite High
Marfan Syndrome 7 70.08 Quite High
Fibrosis 31 68.72 Quite High
Injury 16 56.40 Quite High
Targeted Disruption 7 52.08 Quite High
Immunotherapy Of Cancer 1 51.56 Quite High
Sprains And Strains 8 50.16 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
TSK mutation leads to the production and secretion of a larger mutant FBN-1 protein [14].
Localization (secretion) of FBN-1 in TSK
1) Confidence 0.69 Published 2008 Journal Radiat Oncol Section Body Doc Link PMC2599892 Disease Relevance 1.02 Pain Relevance 0.19
A previous study [12] showed that fibrillin-1 and fibulin-2 were co-localized in the same tissues of the body, and it was suggested that fibrillin-1 assumes the functions of fibulin-2 if the physiological conditions permit.
Localization (localized) of fibrillin-1 in body
2) Confidence 0.52 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1794134 Disease Relevance 0.10 Pain Relevance 0

General Comments

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