INT202978

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Context Info
Confidence 0.50
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 11
Total Number 12
Disease Relevance 13.46
Pain Relevance 4.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (STC2) cell-cell signaling (STC2)
Anatomy Link Frequency
endothelial cells 2
brain 2
STC2 (Homo sapiens)
Pain Link Frequency Relevance Heat
cva 1364 100.00 Very High Very High Very High
anesthesia 10 80.64 Quite High
epidural 20 79.44 Quite High
ischemia 10 70.88 Quite High
cerebral cortex 40 64.80 Quite High
agonist 20 50.36 Quite High
imagery 12 48.40 Quite Low
Dopamine 10 34.72 Quite Low
Deep tissue 10 20.04 Low Low
positron emission tomography 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cv General 3 Under Development 1332 100.00 Very High Very High Very High
Cancer 150 100.00 Very High Very High Very High
Brain Injury 260 99.56 Very High Very High Very High
Head Trauma 50 99.46 Very High Very High Very High
Ovarian Cancer 200 98.76 Very High Very High Very High
Injury 122 97.88 Very High Very High Very High
Coma 40 97.20 Very High Very High Very High
Cerebral Hypoxia 50 97.16 Very High Very High Very High
Disease 28 95.60 Very High Very High Very High
Contusions 10 94.88 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Finally, high expression of new tumor vascular markers, like STC2, EGFL6, and FZD10, which are specifically expressed by tumors harboring tumor endothelial cells, have been shown to be associated with a significant decrease in disease-free interval [147].
Gene_expression (expression) of STC2 in endothelial cells associated with cancer and disease
1) Confidence 0.50 Published 2010 Journal Journal of Oncology Section Body Doc Link PMC2804796 Disease Relevance 0.88 Pain Relevance 0
Finally, high expression of new tumor vascular markers, like STC2, EGFL6, and FZD10, which are specifically expressed by tumors harboring tumor endothelial cells, have been shown to be associated with a significant decrease in disease-free interval [147].
Gene_expression (expressed) of STC2 in endothelial cells associated with cancer and disease
2) Confidence 0.39 Published 2010 Journal Journal of Oncology Section Body Doc Link PMC2804796 Disease Relevance 0.94 Pain Relevance 0
With increased ICP or decreased CPP, StcO2 is reduced.
Gene_expression (reduced) of StcO2 associated with cva
3) Confidence 0.04 Published 2006 Journal Crit Care Section Body Doc Link PMC1794465 Disease Relevance 1.63 Pain Relevance 0.56
ICP, CPP, BIS and StcO2 rates are: ICP ?
Gene_expression (rates) of StcO2 associated with cva
4) Confidence 0.03 Published 2006 Journal Crit Care Section Body Doc Link PMC1794465 Disease Relevance 0.80 Pain Relevance 0.36
The ICP, MAP, BIS, and StcO2 values were recorded hourly for each of the first six post-injury days.
Gene_expression (values) of StcO2 associated with injury and cva
5) Confidence 0.03 Published 2006 Journal Crit Care Section Body Doc Link PMC1794465 Disease Relevance 1.23 Pain Relevance 0.29
Combined BIS and StcO2 rates are: BIS ?
Gene_expression (rates) of StcO2
6) Confidence 0.03 Published 2006 Journal Crit Care Section Body Doc Link PMC1794465 Disease Relevance 0.84 Pain Relevance 0.39
BIS, StcO2, ICP, and CPP are related, but distinct indices of outcome with severe brain injury.
Gene_expression (related) of StcO2 in brain associated with cva and brain injury
7) Confidence 0.03 Published 2006 Journal Crit Care Section Body Doc Link PMC1794465 Disease Relevance 1.39 Pain Relevance 0.58
The hourly StcO2 and BIS values did not influence treatment decisions.
Gene_expression (values) of StcO2
8) Confidence 0.03 Published 2006 Journal Crit Care Section Body Doc Link PMC1794465 Disease Relevance 0.44 Pain Relevance 0.08
Surviving patients and patients with good neurological outcome have higher BIS and StcO2 values.
Gene_expression (values) of StcO2
9) Confidence 0.03 Published 2006 Journal Crit Care Section Body Doc Link PMC1794465 Disease Relevance 1.18 Pain Relevance 0.55
With a BIS <60 and StcO2 <70 an ICP monitor is indicated.
Gene_expression (<60) of StcO2 associated with cva
10) Confidence 0.03 Published 2006 Journal Crit Care Section Body Doc Link PMC1794465 Disease Relevance 1.95 Pain Relevance 0.58
The study purpose is to determine the relationships between StcO2 and BIS values in severe brain injury and ICU outcomes (survival, discharge Glasgow Coma Scale (GCS) score, ICP, CPP, and interventions to lower ICP).


Gene_expression (values) of StcO2 in brain associated with cva, coma and brain injury
11) Confidence 0.03 Published 2006 Journal Crit Care Section Body Doc Link PMC1794465 Disease Relevance 1.29 Pain Relevance 0.40
A frontal subdural hematoma may interfere with BIS or StcO2 values.
Gene_expression (values) of StcO2 associated with head trauma
12) Confidence 0.03 Published 2006 Journal Crit Care Section Body Doc Link PMC1794465 Disease Relevance 0.90 Pain Relevance 0.28

General Comments

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