INT203016

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Context Info
Confidence 0.68
First Reported 2006
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 1.19
Pain Relevance 1.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (CCK, PYY) extracellular region (CCK, PYY) cell proliferation (PYY)
signal transduction (CCK) cytoskeleton organization (PYY) cell-cell signaling (PYY)
Anatomy Link Frequency
proximal 2
CCK (Homo sapiens)
PYY (Homo sapiens)
Pain Link Frequency Relevance Heat
Cholecystokinin 292 100.00 Very High Very High Very High
antagonist 14 80.36 Quite High
Opioid 6 74.48 Quite High
nud 4 65.68 Quite High
Inflammation 10 5.00 Very Low Very Low Very Low
cytokine 6 5.00 Very Low Very Low Very Low
Morphine 4 5.00 Very Low Very Low Very Low
Neuropeptide 4 5.00 Very Low Very Low Very Low
Versed 4 5.00 Very Low Very Low Very Low
spastic colon 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Critical Illness 182 92.20 High High
Obesity 10 83.92 Quite High
Body Weight 10 75.28 Quite High
Dyspepsia 4 65.68 Quite High
Gastric Motility Disorder 16 64.44 Quite High
Appetite Loss 8 55.52 Quite High
Eating Disorder 4 54.08 Quite High
Hypoglycemia 2 50.96 Quite High
Sleep Disorders 10 5.00 Very Low Very Low Very Low
INFLAMMATION 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Consistent with our recent study [29], the postprandial release of PYY is related to the release of CCK, which supports the concept that CCK is an important proximal mediator for the release of PYY [9,10].
CCK Positive_regulation (mediator) of Localization (release) of PYY in proximal associated with cholecystokinin
1) Confidence 0.68 Published 2007 Journal Crit Care Section Body Doc Link PMC2246231 Disease Relevance 0.21 Pain Relevance 0.21
CCK has also been reported to mediate the initial postprandial release of PYY [9,10].
CCK Positive_regulation (mediate) of Localization (release) of PYY associated with cholecystokinin
2) Confidence 0.46 Published 2007 Journal Crit Care Section Body Doc Link PMC2246231 Disease Relevance 0.11 Pain Relevance 0.42
Furthermore, because the release of PYY is influenced by CCK, an elevated response would be associated with enhanced CCK secretion.


CCK Positive_regulation (influenced) of Localization (release) of PYY associated with cholecystokinin
3) Confidence 0.45 Published 2006 Journal Crit Care Section Body Doc Link PMC1794491 Disease Relevance 0.61 Pain Relevance 0.28
The initial release of PYY after food intake [2,9] is likely to be mediated by CCK [9] and its subsequent release is likely to be mediated through stimulation of PYY-secreting cells by luminal nutrients [9].
CCK Positive_regulation (mediated) of Localization (release) of PYY associated with cholecystokinin
4) Confidence 0.37 Published 2006 Journal Crit Care Section Body Doc Link PMC1794491 Disease Relevance 0.25 Pain Relevance 0.25

General Comments

This test has worked.

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