INT203033

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Context Info
Confidence 0.15
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.29
Pain Relevance 0.56

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Cnr1, Cnr2) signal transducer activity (Cnr1, Cnr2) aging (Cnr1)
response to stress (Cnr1)
Anatomy Link Frequency
joint 1
Cnr1 (Rattus norvegicus)
Cnr2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
agonist 4 99.96 Very High Very High Very High
Cannabinoid 3 97.08 Very High Very High Very High
Antinociceptive 2 91.64 High High
Endocannabinoid 3 87.64 High High
nociceptor 18 82.88 Quite High
Pain 78 80.08 Quite High
Arthritis 29 61.16 Quite High
Calcitonin gene-related peptide 10 49.36 Quite Low
COX-2 inhibitor 1 47.24 Quite Low
aspirin 1 43.68 Quite Low
Disease Link Frequency Relevance Heat
Nociception 29 86.44 High High
Pain 57 80.08 Quite High
Arthritis 38 61.16 Quite High
INFLAMMATION 31 40.40 Quite Low
Arthralgia 19 21.92 Low Low
Chronic Renal Failure 1 14.48 Low Low
Hypertension 1 13.44 Low Low
Myocardial Infarction 1 12.88 Low Low
Injury 9 5.00 Very Low Very Low Very Low
Hyperalgesia 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Experiments are currently underway to test the role of selective CB1 and CB2 agonists on joint mechanosensitivity to determine whether a differential response exists between these two receptor subtypes.
CB1 Regulation (role) of CB2 in joint associated with agonist
1) Confidence 0.15 Published 2006 Journal Arthritis Res Ther Section Body Doc Link PMC1794504 Disease Relevance 0.29 Pain Relevance 0.56

General Comments

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