INT203069

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Context Info
Confidence 0.03
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.39
Pain Relevance 0.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Jun) aging (Jun) nucleus (Jun)
DNA binding (Jun) transcription factor binding (Jun)
Anatomy Link Frequency
chondrocytes 2
Jun (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 20 89.72 High High
Osteoarthritis 23 22.60 Low Low
Pain 3 20.88 Low Low
cytokine 10 16.20 Low Low
Arthritis 4 5.00 Very Low Very Low Very Low
chemokine 3 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Paracetamol 1 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 1 92.96 High High
INFLAMMATION 22 89.72 High High
Death 1 66.56 Quite High
Insulin Resistance 1 24.64 Low Low
Osteoarthritis 23 22.60 Low Low
Pain 2 20.88 Low Low
Pathologic Processes 1 14.24 Low Low
Arthritis 11 5.00 Very Low Very Low Very Low
Necrosis 1 5.00 Very Low Very Low Very Low
Aspergillus Infection 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In previous work, however, glucosamine did not appear to inhibit nuclear translocation of activator protein 1 following stimulation of chondrocytes with IL-1 [22]; however, the relationship between this signaling pathway and glucosamine has not been studied in detail.
Negative_regulation (inhibit) of Localization (translocation) of activator protein 1 in chondrocytes
1) Confidence 0.03 Published 2006 Journal Arthritis Res Ther Section Body Doc Link PMC1794517 Disease Relevance 0.39 Pain Relevance 0.11

General Comments

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