INT203087

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Context Info
Confidence 0.05
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.65
Pain Relevance 0.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Il1a, Myd88) extracellular space (Il1a) extracellular region (Il1a)
plasma membrane (Myd88) intracellular (Myd88) protein complex (Myd88)
Il1a (Rattus norvegicus)
Myd88 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 20 92.08 High High
Osteoarthritis 23 64.36 Quite High
Pain 3 62.64 Quite High
cytokine 10 57.96 Quite High
cINOD 1 39.28 Quite Low
Paracetamol 1 37.64 Quite Low
Arthritis 4 5.00 Very Low Very Low Very Low
chemokine 3 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 22 92.08 High High
Death 1 85.36 High High
Osteoarthritis 23 64.36 Quite High
Pain 2 62.64 Quite High
Pathologic Processes 1 56.00 Quite High
Arthritis 11 36.60 Quite Low
Stress 1 32.64 Quite Low
Insulin Resistance 1 5.00 Very Low Very Low Very Low
Necrosis 1 5.00 Very Low Very Low Very Low
Aspergillus Infection 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Ligand binding of these receptors leads to activation of Myd88, IL-1 receptor-activated kinases, and TNF receptor-associated factor 6, which in turn activates cytosolic NF-?
IL-1 Binding (receptor) of Myd88
1) Confidence 0.05 Published 2006 Journal Arthritis Res Ther Section Body Doc Link PMC1794517 Disease Relevance 0.65 Pain Relevance 0.31

General Comments

This test has worked.

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