INT203088

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Context Info
Confidence 0.03
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.26
Pain Relevance 0.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il1a, Mmp3) extracellular region (Il1a, Mmp3) cytosol (Il1a)
peptidase activity (Mmp3) proteinaceous extracellular matrix (Mmp3) nucleus (Mmp3)
Il1a (Rattus norvegicus)
Mmp3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
chemokine 3 95.28 Very High Very High Very High
cytokine 10 94.80 High High
Inflammation 20 94.40 High High
Osteoarthritis 23 76.88 Quite High
Arthritis 4 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Paracetamol 1 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 22 94.40 High High
Arthritis 11 87.04 High High
Osteoarthritis 23 76.88 Quite High
Pain 2 5.00 Very Low Very Low Very Low
Insulin Resistance 1 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low
Necrosis 1 5.00 Very Low Very Low Very Low
Pathologic Processes 1 5.00 Very Low Very Low Very Low
Aspergillus Infection 1 5.00 Very Low Very Low Very Low
Arthralgia 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It also blocked the IL-1-induced expression of matrix-specific proteases such as MMP-3, MMP-9, MMP-10, MMP-12, and ADAMTS-1.
IL-1 Positive_regulation (induced) of Gene_expression (expression) of MMP-3
1) Confidence 0.03 Published 2006 Journal Arthritis Res Ther Section Abstract Doc Link PMC1794517 Disease Relevance 0.26 Pain Relevance 0.18

General Comments

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