INT203101

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Context Info
Confidence 0.25
First Reported 2006
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.24
Pain Relevance 0.88

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Mtx1) nucleus (Aes)
Aes (Mus musculus)
Mtx1 (Mus musculus)
Pain Link Frequency Relevance Heat
methotrexate 83 100.00 Very High Very High Very High
Etanercept 54 98.00 Very High Very High Very High
Infliximab 54 97.40 Very High Very High Very High
withdrawal 10 93.68 High High
tolerance 1 87.32 High High
Leflunomide 2 58.68 Quite High
adenocard 14 50.00 Quite Low
rheumatoid arthritis 10 50.00 Quite Low
Arthritis 4 25.04 Quite Low
Inflammation 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 26 99.64 Very High Very High Very High
Disease 20 29.60 Quite Low
Anxiety Disorder 1 5.04 Very Low Very Low Very Low
Toxicity 5 5.00 Very Low Very Low Very Low
Vomiting 5 5.00 Very Low Very Low Very Low
INFLAMMATION 5 5.00 Very Low Very Low Very Low
Arthritis 3 5.00 Very Low Very Low Very Low
Necrosis 3 5.00 Very Low Very Low Very Low
Cardiovascular Disease 3 5.00 Very Low Very Low Very Low
Diabetes Mellitus 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In summary, we report a novel association between ADORA2a polymorphisms and AEs in MTX-treated RA patients.
AEs Binding (association) of MTX associated with rheumatoid arthritis and methotrexate
1) Confidence 0.25 Published 2008 Journal Rheumatology (Oxford, England) Section Body Doc Link PMC2468887 Disease Relevance 0.24 Pain Relevance 0.21
In addition, the positive impact of concomitant MTX was also associated primarily with fewer dropouts because of AEs.
AEs Binding (associated) of MTX associated with methotrexate
2) Confidence 0.17 Published 2006 Journal Arthritis Res Ther Section Body Doc Link PMC1794519 Disease Relevance 0 Pain Relevance 0.67

General Comments

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