INT203103

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Context Info
Confidence 0.02
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 1.31
Pain Relevance 1.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (ACAN, IL10) extracellular space (IL10) cell adhesion (ACAN)
proteinaceous extracellular matrix (ACAN) intracellular (IL10) cell-cell signaling (IL10)
ACAN (Homo sapiens)
IL10 (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 70 100.00 Very High Very High Very High
cytokine 46 96.28 Very High Very High Very High
Arthritis 206 94.92 High High
Inflammation 14 46.72 Quite Low
rheumatoid arthritis 20 5.00 Very Low Very Low Very Low
spinal inflammation 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Juvenile Chronic Polyarthritis 180 94.92 High High
Disease 48 85.44 High High
Arthritis 8 46.72 Quite Low
Autoimmune Disease 6 44.96 Quite Low
Experimental Arthritis 20 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 20 5.00 Very Low Very Low Very Low
INFLAMMATION 12 5.00 Very Low Very Low Very Low
Necrosis 4 5.00 Very Low Very Low Very Low
Cancer 4 5.00 Very Low Very Low Very Low
Low Back Pain 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
(aggrecan/MMP-3) and interleukin (IL)-17 (aggrecan) and inhibition of IL-10 production (aggrecan).
aggrecan Negative_regulation (inhibition) of Gene_expression (production) of IL-10 associated with metalloproteinase
1) Confidence 0.02 Published 2006 Journal Arthritis Res Ther Section Abstract Doc Link PMC1794523 Disease Relevance 0.63 Pain Relevance 0.55
(aggrecan/MMP-3) and interleukin (IL)-17 (aggrecan) and inhibition of IL-10 production (aggrecan).
aggrecan Negative_regulation (inhibition) of Gene_expression (production) of IL-10 associated with metalloproteinase
2) Confidence 0.02 Published 2006 Journal Arthritis Res Ther Section Abstract Doc Link PMC1794523 Disease Relevance 0.69 Pain Relevance 0.56

General Comments

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