INT203166

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.00
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.65
Pain Relevance 0.34

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (CPOX) small molecule metabolic process (CPOX) oxidoreductase activity (CPOX)
plasma membrane (LTB4R) signal transducer activity (LTB4R) cytoplasm (CPOX)
Anatomy Link Frequency
osteoblasts 3
CPOX (Homo sapiens)
LTB4R (Homo sapiens)
Pain Link Frequency Relevance Heat
Osteoarthritis 105 100.00 Very High Very High Very High
COX-2 inhibitor 3 97.12 Very High Very High Very High
Inflammation 5 68.68 Quite High
cINOD 8 38.24 Quite Low
Analgesic 1 37.32 Quite Low
Pain 2 23.16 Low Low
corticosteroid 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Osteoarthritis 106 100.00 Very High Very High Very High
INFLAMMATION 8 68.68 Quite High
Hypercalcemia 5 65.72 Quite High
Pain 2 23.16 Low Low
Osteoporosis 5 5.00 Very Low Very Low Very Low
Osteophyte 2 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low
Sclerosis 2 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low
Metabolic Disorder 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Moreover, chronic inhibition of COX-2 with a selective inhibitor such as NS-398 in OA osteoblasts enhanced the production of leukotriene B4 (LTB4) [12], a situation also observed in other cell systems using selective COX-2 inhibitors [24].
Negative_regulation (inhibition) of COX in osteoblasts Positive_regulation (enhanced) of Gene_expression (production) of LTB4 in osteoblasts associated with cox-2 inhibitor and osteoarthritis
1) Confidence 0.00 Published 2006 Journal Arthritis Res Ther Section Body Doc Link PMC1794527 Disease Relevance 0.65 Pain Relevance 0.34

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox