INT203170

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Context Info
Confidence 0.01
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.53
Pain Relevance 0.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (CPOX, ALOX5) oxidoreductase activity (CPOX, ALOX5) cytoplasm (CPOX, ALOX5)
cytosol (ALOX5) nuclear envelope (ALOX5) mitochondrion (CPOX)
CPOX (Homo sapiens)
ALOX5 (Homo sapiens)
Pain Link Frequency Relevance Heat
COX-2 inhibitor 3 99.12 Very High Very High Very High
Osteoarthritis 105 93.20 High High
Inflammation 5 59.20 Quite High
cINOD 8 28.76 Quite Low
Analgesic 1 27.84 Quite Low
Pain 2 13.68 Low Low
corticosteroid 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Osteoarthritis 106 93.20 High High
INFLAMMATION 8 59.20 Quite High
Hypercalcemia 5 56.24 Quite High
Pain 2 13.68 Low Low
Osteoporosis 5 5.00 Very Low Very Low Very Low
Osteophyte 2 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low
Sclerosis 2 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low
Metabolic Disorder 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Hence, chronic inhibition of COX-2 may promote abnormal 5-LO activity.
Negative_regulation (inhibition) of COX Positive_regulation (promote) of 5-LO
1) Confidence 0.01 Published 2006 Journal Arthritis Res Ther Section Body Doc Link PMC1794527 Disease Relevance 0.53 Pain Relevance 0.29

General Comments

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