INT203177

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.00
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.72
Pain Relevance 0.46

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (CPOX) small molecule metabolic process (CPOX) oxidoreductase activity (CPOX)
cytoplasm (CPOX)
Anatomy Link Frequency
osteoblasts 3
CPOX (Homo sapiens)
Lts1 (Mus musculus)
Pain Link Frequency Relevance Heat
Osteoarthritis 105 98.32 Very High Very High Very High
Inflammation 5 97.60 Very High Very High Very High
cINOD 8 65.92 Quite High
COX-2 inhibitor 3 60.40 Quite High
Inflammatory response 1 46.44 Quite Low
Pain 2 26.44 Quite Low
corticosteroid 1 5.00 Very Low Very Low Very Low
Analgesic 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Osteoarthritis 106 98.32 Very High Very High Very High
INFLAMMATION 8 97.60 Very High Very High Very High
Pain 2 26.44 Quite Low
Hypercalcemia 5 5.00 Very Low Very Low Very Low
Osteoporosis 5 5.00 Very Low Very Low Very Low
Osteophyte 2 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low
Sclerosis 2 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low
Metabolic Disorder 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These results indicate that the balance of PGE2 levels in OA osteoblasts is actually driving the expression of LTs, and conversely that chronic inhibition of COX may be leading to the synthesis of LTs.
Negative_regulation (inhibition) of COX in osteoblasts Positive_regulation (leading) of Gene_expression (synthesis) of LTs in osteoblasts associated with osteoarthritis
1) Confidence 0.00 Published 2006 Journal Arthritis Res Ther Section Body Doc Link PMC1794527 Disease Relevance 0.72 Pain Relevance 0.46

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox