INT203256

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Context Info
Confidence 0.57
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 2.82
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Xiap) nucleus (Xiap) intracellular (Xiap)
protein complex (Xiap) ligase activity (Xiap) cytoplasm (Xiap)
Xiap (Mus musculus)
Pain Link Frequency Relevance Heat
depression 4 5.00 Very Low Very Low Very Low
headache 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Nevus 88 99.28 Very High Very High Very High
Malignant Neoplastic Disease 40 99.20 Very High Very High Very High
Melanoma 292 94.52 High High
Cancer 104 81.72 Quite High
Ovarian Cancer 40 73.16 Quite High
Apoptosis 84 63.84 Quite High
Disease 20 39.84 Quite Low
Metastasis 12 5.00 Very Low Very Low Very Low
Toxicity 12 5.00 Very Low Very Low Very Low
Death 12 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Changes in XIAP expression corresponded to increases in activity of caspases -3, -8 and -9 (Figure 6A).
Regulation (Changes) of Gene_expression (expression) of XIAP
1) Confidence 0.57 Published 2007 Journal J Transl Med Section Body Doc Link PMC1796544 Disease Relevance 0.27 Pain Relevance 0
We then studied the effect of Phenoxodiol on XIAP expression and function in one of the two Phenoxodiol sensitive cell lines, YUMAC, and in the resistant cells (YUSAC2).
Regulation (effect) of Gene_expression (expression) of XIAP
2) Confidence 0.49 Published 2007 Journal J Transl Med Section Body Doc Link PMC1796544 Disease Relevance 0.47 Pain Relevance 0
Given that these benign nevi were excised, we cannot assess the association between XIAP expression and clinical outcome in nevi.
Regulation (association) of Gene_expression (expression) of XIAP associated with nevus
3) Confidence 0.41 Published 2007 Journal J Transl Med Section Body Doc Link PMC1796544 Disease Relevance 1.33 Pain Relevance 0
We assessed the differences in XIAP expression between benign and malignant tissue.
Regulation (differences) of Gene_expression (expression) of XIAP associated with malignant neoplastic disease
4) Confidence 0.36 Published 2007 Journal J Transl Med Section Body Doc Link PMC1796544 Disease Relevance 0.75 Pain Relevance 0

General Comments

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