INT203258

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Context Info
Confidence 0.39
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.02
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Xiap) nucleus (Xiap) intracellular (Xiap)
protein complex (Xiap) ligase activity (Xiap) cytoplasm (Xiap)
Xiap (Mus musculus)
Pain Link Frequency Relevance Heat
depression 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ovarian Cancer 10 96.36 Very High Very High Very High
Targeted Disruption 2 92.32 High High
Melanoma 73 88.12 High High
Toxicity 3 82.68 Quite High
Death 3 74.12 Quite High
Cancer 26 64.80 Quite High
Apoptosis 21 64.00 Quite High
Nevus 22 24.36 Low Low
Malignant Neoplastic Disease 10 5.00 Very Low Very Low Very Low
Disease 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The precise target and mechanism of action of Phenoxodiol remain unknown, and XIAP degradation might be a downstream effect of Phenoxodiol, rather than a direct effect of the drug.
Negative_regulation (effect) of Protein_catabolism (degradation) of XIAP
1) Confidence 0.39 Published 2007 Journal J Transl Med Section Body Doc Link PMC1796544 Disease Relevance 1.02 Pain Relevance 0

General Comments

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