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Context Info
Confidence 0.32
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.80
Pain Relevance 0.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Slc12a5) plasma membrane (Slc12a5) intracellular (Slc12a5)
transmembrane transport (Slc12a5)
Slc12a5 (Mus musculus)
Pain Link Frequency Relevance Heat
gABA 3 94.60 High High
Neurotransmitter 2 93.40 High High
hyperexcitability 1 80.08 Quite High
potassium channel 1 78.88 Quite High
Glutamate receptor 1 32.04 Quite Low
Spinal cord 12 5.00 Very Low Very Low Very Low
Inflammation 11 5.00 Very Low Very Low Very Low
Hippocampus 9 5.00 Very Low Very Low Very Low
Inflammatory response 8 5.00 Very Low Very Low Very Low
Central nervous system 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 1 96.88 Very High Very High Very High
Death 19 93.12 High High
Stress 22 81.72 Quite High
Hypersensitivity 2 80.92 Quite High
Motor Neuron Diseases 107 76.32 Quite High
Parkinson's Disease 6 56.12 Quite High
Dystonia 1 55.60 Quite High
Apoptosis 5 35.28 Quite Low
Toxicity 1 19.76 Low Low
Disease 30 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Indeed, down-regulation of SLC12A5 expression together with GABAA receptor-mediated excitation occurs after in-vivo axonal injury [31], and mouse SLC12A5 knockouts suffer severe motor deficits and immediate postnatal death by asphyxiation [32].
Regulation (regulation) of Gene_expression (expression) of SLC12A5 associated with injury and death
1) Confidence 0.32 Published 2007 Journal BMC Genomics Section Body Doc Link PMC1796866 Disease Relevance 0.80 Pain Relevance 0.22

General Comments

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