INT203374

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Context Info
Confidence 0.36
First Reported 2007
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.91
Pain Relevance 0.37

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Aqp1) transmembrane transporter activity (Aqp1) plasma membrane (Aqp1)
nucleus (Aqp1) transmembrane transport (Aqp1) cytoplasm (Aqp1)
Aqp1 (Mus musculus)
Pain Link Frequency Relevance Heat
aspirin 15 98.00 Very High Very High Very High
Central nervous system 3 60.24 Quite High
gABA 3 50.52 Quite High
Neurotransmitter 2 49.32 Quite Low
hyperexcitability 1 36.00 Quite Low
potassium channel 1 34.80 Quite Low
imagery 1 27.48 Quite Low
Inflammation 13 5.00 Very Low Very Low Very Low
Spinal cord 12 5.00 Very Low Very Low Very Low
Hippocampus 9 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Toxicity 1 97.64 Very High Very High Very High
Apoptosis 5 89.92 High High
Motor Neuron Diseases 107 85.08 High High
Death 19 82.96 Quite High
Pressure And Volume Under Development 1 62.64 Quite High
Injury 1 60.56 Quite High
Stress 24 37.64 Quite Low
Hypersensitivity 2 36.84 Quite Low
Neurodegenerative Disease 9 14.48 Low Low
Ganglion Cysts 3 13.60 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Water and solute transport is represented by the up-regulation of AQP1 and SLC14A1.
Positive_regulation (up) of Regulation (regulation) of AQP1
1) Confidence 0.36 Published 2007 Journal BMC Genomics Section Body Doc Link PMC1796866 Disease Relevance 0.91 Pain Relevance 0.06
Results showed that aspirin treatment significantly decreases AQP6 mRNA expression (about 70%, Figure 3), while no significant changes were observed for AQP1, 2, 4 and 7 transcripts under this condition.
Neg (no) Positive_regulation (changes) of Neg (no) Regulation (changes) of AQP1 associated with aspirin
2) Confidence 0.23 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2810475 Disease Relevance 0 Pain Relevance 0.31

General Comments

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