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Context Info
Confidence 0.61
First Reported 2007
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.43
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
spinal cord 1
anterior 1
umbilical vein 1
Hoxb (Mus musculus)
Pain Link Frequency Relevance Heat
Spinal cord 5 98.52 Very High Very High Very High
Pain 2 82.88 Quite High
substantia gelatinosa 2 60.08 Quite High
trigeminal ganglion 66 48.00 Quite Low
Neuropeptide 2 15.48 Low Low
GABA receptor 1 14.40 Low Low
Somatostatin 3 12.92 Low Low
Serotonin 1 10.88 Low Low
gABA 2 9.52 Low Low
Glutamate receptor 1 8.32 Low Low
Disease Link Frequency Relevance Heat
Pain 2 82.88 Quite High
Targeted Disruption 44 77.44 Quite High
Wound Healing 3 61.76 Quite High
Increased Venous Pressure Under Development 3 49.12 Quite Low
Ganglion Cysts 70 48.00 Quite Low
Cancer 2 47.60 Quite Low
Adhesions 1 30.12 Quite Low
Neurodegenerative Disease 6 26.40 Quite Low
Nociception 1 21.76 Low Low
Repression 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Loss of Brn3a expression resulted in increased expression of essentially all of the anterior HoxA, HoxB and HoxC genes, and the changes reached statistical significance (p < 0.005 or p > 0.995, Materials and Methods) for seven genes in this group (Figure 5).
Gene_expression (expression) of HoxB in anterior
1) Confidence 0.61 Published 2007 Journal Neural Develop Section Body Doc Link PMC1796875 Disease Relevance 0.22 Pain Relevance 0
It has long been known that Hoxb expression is higher in the dorsal half of the spinal cord [39].
Gene_expression (expression) of Hoxb in spinal cord associated with spinal cord
2) Confidence 0.49 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2527684 Disease Relevance 0.08 Pain Relevance 0.16
For example, 8 of the 10 human HOXB genes were found expressed in cultured umbilical vein ECs and this expression could be modulated by vascular signaling molecules including tissue plasminogen activator (TPA), and vascular endothelial growth factor (VEGF) [8].
Gene_expression (expressed) of HOXB in umbilical vein
3) Confidence 0.25 Published 2008 Journal BMC Dev Biol Section Body Doc Link PMC2570687 Disease Relevance 0.13 Pain Relevance 0

General Comments

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