INT203492

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Context Info
Confidence 0.36
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.68
Pain Relevance 0.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Pou4f1) DNA binding (Pou4f1)
Anatomy Link Frequency
spinal 2
Pou4f1 (Mus musculus)
Pain Link Frequency Relevance Heat
trigeminal ganglion 66 89.16 High High
Central nervous system 5 5.00 Very Low Very Low Very Low
Spinal cord 3 5.00 Very Low Very Low Very Low
Neurotransmitter 3 5.00 Very Low Very Low Very Low
Somatostatin 3 5.00 Very Low Very Low Very Low
midbrain 2 5.00 Very Low Very Low Very Low
Neuropeptide 2 5.00 Very Low Very Low Very Low
gABA 2 5.00 Very Low Very Low Very Low
medulla 2 5.00 Very Low Very Low Very Low
cerebral cortex 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 18 99.96 Very High Very High Very High
Repression 4 97.72 Very High Very High Very High
Ganglion Cysts 70 89.16 High High
Neurodegenerative Disease 6 5.00 Very Low Very Low Very Low
Nociception 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Adhesions 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The failure of DRG neurons to increase NeuroD4 and Tcfap2b expression in Brn3a knockout ganglia suggests that a redundant mechanism of repression exists for these genes at spinal but not cranial levels.
Negative_regulation (failure) of Positive_regulation (increase) of Brn3a in spinal associated with targeted disruption and repression
1) Confidence 0.36 Published 2007 Journal Neural Develop Section Body Doc Link PMC1796875 Disease Relevance 0.68 Pain Relevance 0.11

General Comments

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