INT203495

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Context Info
Confidence 0.67
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.35
Pain Relevance 0.37

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Slc6a1) plasma membrane (Slc6a1)
Slc6a1 (Mus musculus)
Pain Link Frequency Relevance Heat
Somatostatin 3 100.00 Very High Very High Very High
Neuropeptide 2 100.00 Very High Very High Very High
Serotonin 1 100.00 Very High Very High Very High
gABA 2 99.72 Very High Very High Very High
GABA receptor 1 99.60 Very High Very High Very High
Glutamate receptor 1 99.12 Very High Very High Very High
trigeminal ganglion 66 52.76 Quite High
midbrain 2 45.44 Quite Low
Central nervous system 5 33.80 Quite Low
Spinal cord 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Nociception 1 84.32 Quite High
Neurodegenerative Disease 6 75.12 Quite High
Targeted Disruption 18 74.16 Quite High
Adhesions 1 67.36 Quite High
Ganglion Cysts 70 52.76 Quite High
Repression 4 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Among mediators of neurotransmission, multiple glutamate receptors (Gria3, Gria4, Grik1), a GABA transporter (Slc6a1), a serotonin receptor (Htr3a) and the neuropeptide somatostatin are increased, while a GABA receptor (Gabra2) and neuropeptides with specific sensory roles (Galanin, Adcyap1/PACAP) are decreased.
Positive_regulation (increased) of Slc6a1 associated with gaba, gaba receptor, glutamate receptor, somatostatin, neuropeptide and serotonin
1) Confidence 0.67 Published 2007 Journal Neural Develop Section Body Doc Link PMC1796875 Disease Relevance 0.35 Pain Relevance 0.37

General Comments

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