INT203507

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Context Info
Confidence 0.33
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 2.10
Pain Relevance 0.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Dcc (Mus musculus)
Pain Link Frequency Relevance Heat
Neuropeptide 2 76.16 Quite High
GABA receptor 1 75.08 Quite High
Somatostatin 3 73.60 Quite High
Serotonin 1 71.56 Quite High
gABA 2 70.20 Quite High
Glutamate receptor 1 69.00 Quite High
trigeminal ganglion 66 23.52 Low Low
midbrain 2 16.20 Low Low
Central nervous system 5 5.00 Very Low Very Low Very Low
Spinal cord 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 11 100.00 Very High Very High Very High
Increased Venous Pressure Under Development 2 98.76 Very High Very High Very High
Cardiovascular Disease 6 97.52 Very High Very High Very High
Stress 1 93.36 High High
Adhesions 1 90.80 High High
Hypoxia 1 89.68 High High
Congenital Anomalies 1 89.36 High High
Neurodegenerative Disease 6 87.08 High High
Embryonic Lethality 1 86.48 High High
Nociception 1 82.44 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Increased expression was also noted for several molecules with known or likely roles in axon guidance, including Disabled1, Sema3c, Sema3d, f-spondin, Cadherin22, Protocadherin 8, Protocadherin 17, Dcc, and NetrinG1.
Gene_expression (expression) of Dcc
1) Confidence 0.33 Published 2007 Journal Neural Develop Section Body Doc Link PMC1796875 Disease Relevance 0.31 Pain Relevance 0.25
Overexpressed LKB1 increases expression of several p21 (CDK inhibitor), p53 responsive genes.8-11) This tumor suppressor protein may have an important role in atherosclerosis, especially in restenosis.
Gene_expression (expression) of tumor suppressor protein associated with cardiovascular disease, cancer and increased venous pressure under development
2) Confidence 0.01 Published 2010 Journal Korean Circulation Journal Section Body Doc Link PMC3008825 Disease Relevance 1.79 Pain Relevance 0

General Comments

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