INT203557

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Context Info
Confidence 0.31
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.70
Pain Relevance 0.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (NRG1) extracellular space (NRG1) extracellular region (NRG1)
plasma membrane (NRG1) nucleus (NRG1) embryo development (NRG1)
NRG1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Dopamine 1 92.96 High High
withdrawal 3 87.64 High High
interneuron 1 69.04 Quite High
Spinal cord 74 63.44 Quite High
GABAergic 19 62.60 Quite High
Hippocampus 13 47.12 Quite Low
imagery 3 40.40 Quite Low
Neurotransmitter 9 5.00 Very Low Very Low Very Low
anesthesia 4 5.00 Very Low Very Low Very Low
gABA 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Schizophrenia 9 99.40 Very High Very High Very High
Urological Neuroanatomy 1 86.32 High High
Disease 5 81.68 Quite High
Syndrome 1 73.28 Quite High
Intrauterine Growth Retardation 1 66.92 Quite High
Congenital Anomalies 3 42.32 Quite Low
Thyroid Disease 6 21.24 Low Low
Generalized Anxiety Disorder 12 5.00 Very Low Very Low Very Low
Spinal Cord Injury 8 5.00 Very Low Very Low Very Low
Death 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Among NRGs, NRG1 and NRG3 transcripts, particularly the latter, were also found to have significantly increased.
Transcription (transcripts) of NRG1
1) Confidence 0.31 Published 2007 Journal PLoS Medicine Section Body Doc Link PMC1796906 Disease Relevance 0 Pain Relevance 0.10
Furthermore, altered expression of other genes such as nuclear orphan transcription factor Nur-related receptor 1 (Nurr1) (Xing et al. 2006) or Neuregulin 1 is altered in schizophrenia (Harrison and Law 2006; Addington et al. 2007).
Transcription (transcription) of Neuregulin 1 associated with schizophrenia
2) Confidence 0.05 Published 2010 Journal Cerebral Cortex (New York, NY) Section Body Doc Link PMC2871377 Disease Relevance 0.70 Pain Relevance 0.14

General Comments

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