INT203583

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Context Info
Confidence 0.03
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (IL8, TIMP2) signal transduction (IL8) extracellular space (IL8)
intracellular (IL8)
IL8 (Homo sapiens)
TIMP2 (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 11 100.00 Very High Very High Very High
COX-2 inhibitor 6 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Reprotox - General 1 26 50.00 Quite Low
Apoptosis 7 45.88 Quite Low
Death 3 42.40 Quite Low
Cancer 45 32.72 Quite Low
Inflammatory Breast Neoplasms 8 5.00 Very Low Very Low Very Low
Melanoma 5 5.00 Very Low Very Low Very Low
Metastasis 2 5.00 Very Low Very Low Very Low
Advanced Or Metastatic Breast Cancer 2 5.00 Very Low Very Low Very Low
Hypoxia 2 5.00 Very Low Very Low Very Low
Ductal Carcinoma 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The cell culture supernatants of vehicle treated cells had greater amounts of growth related protein (GRO), IL-6, IL-8, tissue inhibitor of matrix metalloproteinase (TIMP)1 and TIMP2, and VEGF, based on gray levels or brightness values as compared with cells treated with celecoxib.
IL-8 Negative_regulation (inhibitor) of TIMP2 associated with metalloproteinase
1) Confidence 0.03 Published 2006 Journal Breast Cancer Res Section Body Doc Link PMC1797025 Disease Relevance 0 Pain Relevance 0.10

General Comments

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