INT203682

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Context Info
Confidence 0.36
First Reported 2004
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 3.71
Pain Relevance 0.74

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

MROS (Homo sapiens)
Pain Link Frequency Relevance Heat
alcohol 9 98.08 Very High Very High Very High
agonist 7 93.68 High High
Dismenorea 1 90.08 High High
depression 47 88.84 High High
ischemia 10 83.08 Quite High
adenocard 15 69.08 Quite High
antagonist 11 66.32 Quite High
anesthesia 2 55.44 Quite High
headache 6 39.40 Quite Low
antidepressant 13 16.44 Low Low
Disease Link Frequency Relevance Heat
Personality Disorder 26 99.84 Very High Very High Very High
Premenstrual Syndrome 14 99.70 Very High Very High Very High
Manic Depressive Disorder 120 98.72 Very High Very High Very High
Reprotox - General 3 26 94.72 High High
Endometriosis (extended) 61 93.36 High High
Hyperemia 43 92.12 High High
Depression 71 88.84 High High
Psychosis 24 86.48 High High
Cv Unclassified Under Development 14 83.08 Quite High
Depressive Disorder 16 75.24 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A history of PMDD significantly predicted MRS scores.
Negative_regulation (predicted) of MRS associated with premenstrual syndrome
1) Confidence 0.36 Published 2010 Journal Journal of Korean Medical Science Section Body Doc Link PMC2858837 Disease Relevance 1.41 Pain Relevance 0.35
B may have been adversely affected by several factors: 1) personality factors such as high Harm Avoidance and low Novelty Seeking and Self-Directedness; 2) Avoidant Personality Disorder, which prevents Mrs.
Negative_regulation (prevents) of Mrs. B associated with personality disorder
2) Confidence 0.05 Published 2007 Journal Ann Gen Psychiatry Section Body Doc Link PMC1797808 Disease Relevance 0.67 Pain Relevance 0.10
The mean decrease in MRS scores for patients with mixed mania in the ziprasidone group was significantly greater than those in the placebo group (p < 0.01 at 14 days and p < 0.05 at 21 days).


Negative_regulation (decrease) of MRS associated with manic depressive disorder
3) Confidence 0.01 Published 2007 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2656324 Disease Relevance 0.88 Pain Relevance 0.03
Two studies of each of 4 drugs (aripiprazole, olanzapine, risperidone and ziprasidone) used 50% reduction in MRS or YMRS as the criteria for response.
Negative_regulation (reduction) of MRS
4) Confidence 0.01 Published 2007 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2656324 Disease Relevance 0.28 Pain Relevance 0
Recently, a selective P2Y1 receptor inhibitor, MRS 2179, has become available [4, 5, 20], facilitating further exploration of these effects.
Negative_regulation (inhibitor) of MRS
5) Confidence 0.01 Published 2004 Journal Purinergic Signal Section Body Doc Link PMC2096564 Disease Relevance 0.47 Pain Relevance 0.26

General Comments

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