INT203729

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Context Info
Confidence 0.27
First Reported 2007
Last Reported 2007
Negated 0
Speculated 3
Reported most in Body
Documents 1
Total Number 5
Disease Relevance 3.83
Pain Relevance 1.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Thbs1)
Anatomy Link Frequency
plasma 1
endothelial cells 1
fibroblasts 1
Thbs1 (Mus musculus)
Pain Link Frequency Relevance Heat
anesthesia 10 84.60 Quite High
isoflurane 10 84.16 Quite High
cytokine 25 81.52 Quite High
Inflammation 220 76.84 Quite High
Inflammatory response 25 59.28 Quite High
chemokine 5 54.64 Quite High
agonist 20 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 805 99.68 Very High Very High Very High
Melanoma 35 94.88 High High
Hemorrhage 5 82.92 Quite High
INFLAMMATION 250 76.84 Quite High
Metastasis 45 51.64 Quite High
Aids-related Complex 5 45.28 Quite Low
Corneal Neovascularization 35 35.12 Quite Low
Lewis Lung Carcinoma 35 5.00 Very Low Very Low Very Low
Liver Cancer 15 5.00 Very Low Very Low Very Low
Atherosclerosis 15 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Because TSP-1 can be expressed in several cell types, including tumor cells, endothelial cells and fibroblasts, we next determined the cellular origin for TSP-1 in the tumors of PPAR?
TSP-1 Spec (determined) Binding (origin) of in fibroblasts associated with cancer
1) Confidence 0.27 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1800345 Disease Relevance 1.38 Pain Relevance 0.21
Total protein extracts (50 µg) were analyzed on blots incubated with primary mouse monoclonal TSP-1 (Ab-11, Lab Vision, Fremont, CA) and HRP-conjugated secondary antibodies (Amersham Biosciences Corp.
TSP-1 Binding (primary) of
2) Confidence 0.24 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1800345 Disease Relevance 0.35 Pain Relevance 0.24
Total protein extracts (50 µg) were analyzed on blots incubated with primary mouse monoclonal TSP-1 (Ab-11, Lab Vision, Fremont, CA) and HRP-conjugated secondary antibodies (Amersham Biosciences Corp.
TSP-1 Spec (analyzed) Binding (incubated) of
3) Confidence 0.24 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1800345 Disease Relevance 0.36 Pain Relevance 0.24
TSP-1 was measured by ELISA (Cytimmune, Rockville, MD) in blood plasma collected from non-tumor bearing PPAR?
TSP-1 Binding (measured) of in plasma associated with cancer
4) Confidence 0.24 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1800345 Disease Relevance 0.37 Pain Relevance 0.21
Because TSP-1 can be expressed in several cell types, including tumor cells, endothelial cells and fibroblasts, we next determined the cellular origin for TSP-1 in the tumors of PPAR?
TSP-1 Spec (determined) Binding (origin) of in endothelial cells associated with cancer
5) Confidence 0.09 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1800345 Disease Relevance 1.38 Pain Relevance 0.21

General Comments

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