INT203748

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Context Info
Confidence 0.41
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 8
Total Number 10
Disease Relevance 0.83
Pain Relevance 0.53

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (STS) nuclear envelope (STS) small molecule metabolic process (STS)
Golgi apparatus (STS) endoplasmic reticulum (STS) plasma membrane (STS)
Anatomy Link Frequency
amygdala 2
liver 1
sulcus 1
face 1
posterior 1
STS (Homo sapiens)
Pain Link Frequency Relevance Heat
amygdala 9 97.56 Very High Very High Very High
antidepressant 75 93.36 High High
depression 66 81.92 Quite High
magnetoencephalography 26 76.32 Quite High
headache 21 70.44 Quite High
cocaine 6 56.00 Quite High
transdermal 60 50.00 Quite Low
insula 29 32.56 Quite Low
imagery 22 11.92 Low Low
Pain 29 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pressure And Volume Under Development 21 89.12 High High
Depression 129 81.92 Quite High
Hypertension 3 73.68 Quite High
Anxiety Disorder 69 72.24 Quite High
Headache 21 70.44 Quite High
Deafness 2 30.96 Quite Low
Cognitive Disorder 19 12.36 Low Low
Recurrence 24 5.00 Very Low Very Low Very Low
Pain 19 5.00 Very Low Very Low Very Low
Sleep Disorders 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Future work should investigate the interactions between action encoding regions such as the STS and its interactions with brain areas involved in emotional encoding such as the amygdala and the orbitofrontal cortex.
STS Binding (interactions) of in amygdala associated with amygdala
1) Confidence 0.41 Published 2010 Journal Quarterly Journal of Experimental Psychology (2006) Section Body Doc Link PMC2988435 Disease Relevance 0 Pain Relevance 0.05
We expected that predictable transitions would engage visual areas including the STS, resulting in heightened activity in these areas, relative to scrambled stimuli.
STS Binding (engage) of
2) Confidence 0.36 Published 2010 Journal Cerebral Cortex (New York, NY) Section Body Doc Link PMC2820709 Disease Relevance 0 Pain Relevance 0.08
The data from these tyramine challenge studies should allay concerns regarding treatment with STS and dietary interactions.
STS Binding (interactions) of
3) Confidence 0.36 Published 2007 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2656289 Disease Relevance 0 Pain Relevance 0.05
Given the unique pharmacokinetic profile of STS (in which transdermally administered selegiline bypasses the gut and liver), studies specifically investigating drug interactions with STS are warranted.
STS Binding (interactions) of in liver
4) Confidence 0.36 Published 2007 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2656289 Disease Relevance 0.32 Pain Relevance 0.14
Future work should investigate the interactions between action encoding regions such as the STS and its interactions with brain areas involved in emotional encoding such as the amygdala and the orbitofrontal cortex.
STS Binding (interactions) of in amygdala associated with amygdala
5) Confidence 0.32 Published 2010 Journal Quarterly Journal of Experimental Psychology (2006) Section Body Doc Link PMC2988435 Disease Relevance 0 Pain Relevance 0.05
The orientation of attention based on observed gaze direction is thought to reflect the activation of neural systems such as the superior temporal sulcus (STS) dedicated to decoding social stimuli (e.g., Perrett et al., 1985, for evidence from monkeys; Hoffman & Haxby, 2000, for humans), and the STS interacts with areas involved in orienting of attention such as the intraparietal sulcus (IPS).
STS Binding (interacts) of in sulcus
6) Confidence 0.31 Published 2010 Journal Quarterly Journal of Experimental Psychology (2006) Section Body Doc Link PMC2988435 Disease Relevance 0 Pain Relevance 0
Similar post-M170 sustained responses have been previously observed in response to facial expressions and associated with STS activity (Furl et al. 2007).
STS Binding (associated) of
7) Confidence 0.27 Published 2010 Journal Cerebral Cortex (New York, NY) Section Body Doc Link PMC2820709 Disease Relevance 0.20 Pain Relevance 0.03
The majority of these studies associate the posterior right STS with socially and behaviourally relevant visual cues, namely biological motion and static images of the face and the body [47].
STS Binding (associate) of in face
8) Confidence 0.21 Published 2007 Journal BMC Neurosci Section Body Doc Link PMC1800857 Disease Relevance 0 Pain Relevance 0
While the latter studies associate the left hemisphere STS with crossmodal representations during audiovisual speech perception, our present finding of dominant activation in the right posterior STS (approximately 40 mm posterior from the anterior commissure) calls for another interpretation.
STS Binding (associate) of in posterior
9) Confidence 0.21 Published 2007 Journal BMC Neurosci Section Body Doc Link PMC1800857 Disease Relevance 0 Pain Relevance 0
Given the unique pharmacokinetic profile of STS (in which transdermally administered selegiline bypasses the gut and liver), studies specifically investigating drug interactions with STS are warranted.
STS Binding (interactions) of in gut
10) Confidence 0.12 Published 2007 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2656289 Disease Relevance 0.32 Pain Relevance 0.14

General Comments

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