INT203827

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Context Info
Confidence 0.32
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.81
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (Apob) extracellular space (Apob) endoplasmic reticulum (Apob)
enzyme binding (Apob) lipid metabolic process (Apob)
Anatomy Link Frequency
liver 1
Apob (Mus musculus)
Pain Link Frequency Relevance Heat
Potency 53 89.20 High High
Inflammation 27 45.12 Quite Low
cytokine 13 5.00 Very Low Very Low Very Low
Bile 7 5.00 Very Low Very Low Very Low
metalloproteinase 4 5.00 Very Low Very Low Very Low
Angina 3 5.00 Very Low Very Low Very Low
chemokine 3 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 22 100.00 Very High Very High Very High
Coronary Artery Disease 12 93.60 High High
Hepatotoxicity 42 87.80 High High
Atherosclerosis 83 86.16 High High
Myocardial Infarction 7 84.56 Quite High
Apoptosis 27 81.84 Quite High
Injury 4 80.52 Quite High
Adhesions 7 79.44 Quite High
Disease 26 74.88 Quite High
Hyperlipoproteinemia Type Ii 66 72.20 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Three active ASO sequences (6, 8 and 9, Table 1) targeting either mouse ApoB or mouse PTEN were identified in cell culture assays using methods previously described for these targets.
Localization (targeting) of ApoB
1) Confidence 0.32 Published 2007 Journal Nucleic Acids Research Section Body Doc Link PMC1802611 Disease Relevance 0.49 Pain Relevance 0.13
Therefore, apoB-48-containing VLDL is secreted from the liver in mice [80,81].
Localization (secreted) of apoB in liver
2) Confidence 0.16 Published 2010 Journal Int Arch Med Section Body Doc Link PMC3016243 Disease Relevance 0.94 Pain Relevance 0
molecule (POVPC) that can oxidise apolipoprotein B (ApoB) as well as other
Localization (oxidise) of ApoB associated with disorder of lipid metabolism
3) Confidence 0.14 Published 2008 Journal Clinical and Developmental Immunology Section Body Doc Link PMC2423423 Disease Relevance 0.38 Pain Relevance 0

General Comments

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