INT203874

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Context Info
Confidence 0.49
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.91
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (GSTP1) small molecule metabolic process (GSTP1) plasma membrane (GSTP1)
nucleus (GSTP1) intracellular (GSTP1) protein complex (GSTP1)
GSTP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Bioavailability 10 11.32 Low Low
antagonist 39 5.00 Very Low Very Low Very Low
Inflammation 15 5.00 Very Low Very Low Very Low
local anesthetic 11 5.00 Very Low Very Low Very Low
agonist 9 5.00 Very Low Very Low Very Low
Angina 7 5.00 Very Low Very Low Very Low
gABA 6 5.00 Very Low Very Low Very Low
depression 5 5.00 Very Low Very Low Very Low
metalloproteinase 5 5.00 Very Low Very Low Very Low
Calcium channel 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Prostate Cancer 15 99.60 Very High Very High Very High
Cancer 225 97.68 Very High Very High Very High
Systemic Lupus Erythematosus 6 95.96 Very High Very High Very High
Nicotine Addiction 5 93.48 High High
Stress 24 88.92 High High
Syndrome 5 84.88 Quite High
Phototoxic Dermatitis 4 76.56 Quite High
Vomiting 6 71.36 Quite High
Heart Rate Under Development 18 68.04 Quite High
Arrhythmia Under Development 2 62.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Table 3 shows the distribution of NAT2, GSTM1, GSTT1, and GSTP1 genotypes by self-reported chemical-related sensitivity score (?
Positive_regulation (shows) of Gene_expression (distribution) of GSTP1
1) Confidence 0.49 Published 2007 Journal Environ Health Section Body Doc Link PMC1802749 Disease Relevance 0.18 Pain Relevance 0
Finally, it was suggested that that cells overexpressing GSTP1-1 could protect neighboring cells from hypericin-dependent PDT by sequestering the photosensitizer.
Positive_regulation (overexpressing) of Gene_expression (overexpressing) of GSTP1-1 associated with cancer
2) Confidence 0.09 Published 2010 Journal International Journal of Molecular Sciences Section Body Doc Link PMC2852855 Disease Relevance 0.62 Pain Relevance 0
Afterward, in 2001 Lin et al. reported that procainamide was able to demethylate and restore GSTP1 gene expression in LNCaP prostatic carcinoma cell line in vitro and in nude mice carrying prostatic carcinoma xenografts [184].
Positive_regulation (restore) of Gene_expression (expression) of GSTP1 gene associated with prostate cancer
3) Confidence 0.03 Published 2008 Journal Mol Cancer Section Body Doc Link PMC2615789 Disease Relevance 1.11 Pain Relevance 0

General Comments

This test has worked.

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