INT204021

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Context Info
Confidence 0.57
First Reported 2007
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 8
Total Number 8
Disease Relevance 2.75
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Gsk3b) carbohydrate metabolic process (Gsk3b) protein complex (Gsk3b)
response to stress (Gsk3b) cytoplasm (Gsk3b) cytosol (Gsk3b)
Anatomy Link Frequency
liver 1
Gsk3b (Mus musculus)
Pain Link Frequency Relevance Heat
Dopamine 6 87.92 High High
Eae 28 75.08 Quite High
tolerance 19 57.92 Quite High
Hippocampus 17 47.80 Quite Low
cerebral cortex 9 47.16 Quite Low
cytokine 4 44.72 Quite Low
Inflammation 11 38.32 Quite Low
Spinal cord 6 5.00 Very Low Very Low Very Low
depression 6 5.00 Very Low Very Low Very Low
imagery 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 144 100.00 Very High Very High Very High
Disease 215 98.00 Very High Very High Very High
Sprains And Strains 44 96.32 Very High Very High Very High
Alagille Syndrome 22 96.00 Very High Very High Very High
Cognitive Disorder 18 94.08 High High
Death 55 92.56 High High
Diabetes Mellitus 25 85.68 High High
Cancer 34 83.48 Quite High
Stomach Cancer 22 80.72 Quite High
Amyloid Plaque 30 61.36 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In particular, the A1.13 clone had barely detectable GSK3?
Transcription (had) of GSK3
1) Confidence 0.57 Published 2007 Journal J Circadian Rhythms Section Body Doc Link PMC1803776 Disease Relevance 0.06 Pain Relevance 0
KO was developed, and here, describe the generation of skeletal muscle- and liver-specific GSK-3?
Transcription (describe) of GSK-3 in liver associated with targeted disruption
2) Confidence 0.53 Published 2011 Journal PLoS ONE Section Body Doc Link PMC3017066 Disease Relevance 1.15 Pain Relevance 0.03
To further study the involvement of GSK-3, transgenic mice that overexpress GSK-3?
Transcription (transgenic mice) of GSK-3 associated with targeted disruption
3) Confidence 0.45 Published 2010 Journal International Journal of Alzheimer's Disease Section Body Doc Link PMC2915753 Disease Relevance 0.70 Pain Relevance 0.04
In this sense, it is interesting that the activity of GSK3?
Transcription (activity) of GSK3
4) Confidence 0.42 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2797305 Disease Relevance 0.25 Pain Relevance 0.08
Considering the narrow concentration range of GSK-3 that permits cell viability, a model was created with GSK-3 gene expression adjustable by means of a conditional tetracycline regulated system under the control of the CaM kinase II ?
Transcription (range) of GSK-3
5) Confidence 0.39 Published 2010 Journal International Journal of Alzheimer's Disease Section Body Doc Link PMC2915753 Disease Relevance 0.15 Pain Relevance 0.08
Interestingly, a strong immunostaining signal for phosphorylated GSK3 was found in a sub-population of Kato-III cells that also showed nuclear accumulation of ?
Transcription (found) of GSK3
6) Confidence 0.31 Published 2008 Journal EMBO J Section Body Doc Link PMC2413189 Disease Relevance 0.45 Pain Relevance 0
No significant effect was shown on the subcellular distribution of total GSK-3?
Transcription (distribution) of GSK-3
7) Confidence 0.24 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2675062 Disease Relevance 0 Pain Relevance 0
These results are consistent with the idea that the Akt-GSK3?
Transcription (idea) of GSK3
8) Confidence 0.09 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2877100 Disease Relevance 0 Pain Relevance 0

General Comments

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