INT204052

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Context Info
Confidence 0.51
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 6
Disease Relevance 3.25
Pain Relevance 0.45

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Bcl2) cell morphogenesis (Bcl2) endoplasmic reticulum (Bcl2)
intracellular (Bcl2) cytoplasm (Bcl2) cell proliferation (Bcl2)
Anatomy Link Frequency
B-cell 2
Bcl2 (Mus musculus)
Pain Link Frequency Relevance Heat
ischemia 15 96.72 Very High Very High Very High
bradykinin 10 96.48 Very High Very High Very High
cva 25 91.80 High High
agonist 5 89.96 High High
Inflammation 26 65.52 Quite High
antagonist 8 51.52 Quite High
cytokine 10 43.52 Quite Low
anesthesia 6 5.00 Very Low Very Low Very Low
Calcium channel 4 5.00 Very Low Very Low Very Low
Inflammatory response 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 209 100.00 Very High Very High Very High
Lymphatic System Cancer 5 100.00 Very High Very High Very High
Death 19 99.26 Very High Very High Very High
Reperfusion Injury 34 98.08 Very High Very High Very High
Cv Unclassified Under Development 15 96.72 Very High Very High Very High
Hemorrhage 25 91.80 High High
Aging 2 90.76 High High
Cancer 82 89.64 High High
Glioblastoma 38 83.64 Quite High
Hemorrhagic Shock 51 70.88 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
SP cells expressed higher levels of the stem cell markers ATP-binding cassette transporter G2 (ABCG2), p75 neurotrophin receptor (p75NTR), nestin (nes), B-cell lymphoma 2 (Bcl2), and cell surface antigen Sca-1 mRNA than the main population cells.
Transcription (expressed) of B-cell lymphoma 2 in B-cell associated with lymphatic system cancer
1) Confidence 0.51 Published 2010 Journal Molecular Vision Section Abstract Doc Link PMC2890558 Disease Relevance 0.19 Pain Relevance 0
SP cells expressed higher levels of the stem cell markers ATP-binding cassette transporter G2 (ABCG2), p75 neurotrophin receptor (p75NTR), nestin (nes), B-cell lymphoma 2 (Bcl2), and cell surface antigen Sca-1 mRNA than the main population cells.
Transcription (expressed) of Bcl2 in B-cell associated with lymphatic system cancer
2) Confidence 0.51 Published 2010 Journal Molecular Vision Section Abstract Doc Link PMC2890558 Disease Relevance 0.19 Pain Relevance 0
Furthermore, protein data of inversely expressed Bax and Bcl-2 protein expression were confirmed by additional analysis of Bax and Bcl-2 mRNA expression using real-time PCR (data not shown).
Transcription (expression) of Bcl-2
3) Confidence 0.44 Published 2008 Journal Crit Care Section Body Doc Link PMC2374615 Disease Relevance 0.69 Pain Relevance 0.15
In agreement with the reduced infectious center titers at later time points, the viral genome load of the vBcl-2??
Transcription (load) of vBcl-2
4) Confidence 0.40 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2752191 Disease Relevance 0.06 Pain Relevance 0
Cell death was estimated by the anti-apoptotic Bcl-2 and the pro-apoptotic Bad mRNA expression and caspase-3 activity, a central protease in apoptosis that is induced by renal ischemia.
Transcription (expression) of Bcl-2 associated with ischemia, apoptosis and death
5) Confidence 0.20 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2516176 Disease Relevance 1.25 Pain Relevance 0.31
Phosphorylation at the N-terminal region of p53 abolishes Mdm2 inhibition, which causes an increase in Bax transcription (Fig. 2c shows that Bax proteins were increased) and an inhibition of Bcl-2 transcription.
Transcription (transcription) of Bcl-2
6) Confidence 0.05 Published 2006 Journal Journal of Neurochemistry Section Body Doc Link PMC1804119 Disease Relevance 0.86 Pain Relevance 0

General Comments

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